Trial Outcomes & Findings for Stryker Triathlon Total Knee System for Total Knee Arthroplasty Implanted Using ShapeMatch® Cutting Guides: Sub-Study B (NCT NCT02527161)

NCT ID: NCT02527161

Last Updated: 2020-09-18

Results Overview

Implant location and limb alignment is assessed using CT scan 3 months after surgery. The mean deviation of the postoperative femoral and tibial alignment from the preoperative plan is measured in degrees.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

205 participants

Primary outcome timeframe

3 months Post-Operatively

Results posted on

2020-09-18

Participant Flow

Patients were assessed and then placed in either Part A or Part B. Patients in Part B were invited to participate in the extension follow-up to 5-years.

Participant milestones

Participant milestones
Measure
ShapeMatch® Cutting Guides With Triathlon®
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Overall Study
STARTED
205
Overall Study
COMPLETED
73
Overall Study
NOT COMPLETED
132

Reasons for withdrawal

Reasons for withdrawal
Measure
ShapeMatch® Cutting Guides With Triathlon®
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Overall Study
Failed MRI
52
Overall Study
Withdrawal by Subject
19
Overall Study
Delay in or unfit for surgery
16
Overall Study
MRI contraindication
6
Overall Study
Consent violation
4
Overall Study
Only Recruited to Part A
27
Overall Study
Physician Decision
1
Overall Study
Adverse Event
1
Overall Study
Lost to Follow-up
6

Baseline Characteristics

Stryker Triathlon Total Knee System for Total Knee Arthroplasty Implanted Using ShapeMatch® Cutting Guides: Sub-Study B

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
ShapeMatch Cutting Guides With Triathlon
n=96 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Age, Continuous
68.04 years
STANDARD_DEVIATION 8.30 • n=5 Participants
Sex: Female, Male
Female
34 Participants
n=5 Participants
Sex: Female, Male
Male
62 Participants
n=5 Participants
Region of Enrollment
Australia
96 participants
n=5 Participants

PRIMARY outcome

Timeframe: 3 months Post-Operatively

Population: Participants with available data. Participants=knees.

Implant location and limb alignment is assessed using CT scan 3 months after surgery. The mean deviation of the postoperative femoral and tibial alignment from the preoperative plan is measured in degrees.

Outcome measures

Outcome measures
Measure
ShapeMatch Cutting Guides With Triathlon
n=95 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Implant Location/Assessment of Alignment
Femoral deviation pre-op to post-op
1.70 degrees
Standard Deviation 1.46
Implant Location/Assessment of Alignment
Tibial deviation pre-op to post-op
1.91 degrees
Standard Deviation 1.58

SECONDARY outcome

Timeframe: Pre-operative to 5 years post-operative

Population: Participants with available data. Participants=knees.

KOOS consists of 5 subscales; Pain, other Symptoms, Function in daily living (ADL), Function in sport and recreation (Sport/Rec) and knee related Quality of life (QOL). The last week is taken into consideration when answering the questions. Standardized answer options are given (5 Likert boxes) and each question gets a score from 0 to 4. A normalized score (100 indicating no symptoms and 0 indicating extreme symptoms) is calculated for each subscale.)

Outcome measures

Outcome measures
Measure
ShapeMatch Cutting Guides With Triathlon
n=100 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Knee Injury and Osteoarthritis Outcome Score (KOOS)_Pain
Pre-op KOOS Pain score
36.18 units on a scale
Standard Deviation 17.64
Knee Injury and Osteoarthritis Outcome Score (KOOS)_Pain
6 weeks KOOS Pain score
66.23 units on a scale
Standard Deviation 16.88
Knee Injury and Osteoarthritis Outcome Score (KOOS)_Pain
3 months KOOS Pain score
74.96 units on a scale
Standard Deviation 18.55
Knee Injury and Osteoarthritis Outcome Score (KOOS)_Pain
6 months KOOS Pain score
80.03 units on a scale
Standard Deviation 18.12
Knee Injury and Osteoarthritis Outcome Score (KOOS)_Pain
1 year KOOS Pain score
85.11 units on a scale
Standard Deviation 16.69
Knee Injury and Osteoarthritis Outcome Score (KOOS)_Pain
2 years KOOS Pain score
87.00 units on a scale
Standard Deviation 18.18
Knee Injury and Osteoarthritis Outcome Score (KOOS)_Pain
5 years KOOS Pain score
89.58 units on a scale
Standard Deviation 14.24

SECONDARY outcome

Timeframe: Pre-operative to 5 years post-operative

Population: Participants with available data. Participants=knees

KOOS consists of 5 subscales; Pain, other Symptoms, Function in daily living (ADL), Function in sport and recreation (Sport/Rec) and knee related Quality of life (QOL). The last week is taken into consideration when answering the questions. Standardized answer options are given (5 Likert boxes) and each question gets a score from 0 to 4. A normalized score (100 indicating no symptoms and 0 indicating extreme symptoms) is calculated for each subscale.)

Outcome measures

Outcome measures
Measure
ShapeMatch Cutting Guides With Triathlon
n=100 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Knee Injury and Osteoarthritis Outcome Score (KOOS)_Symptoms
Pre-op KOOS Symptoms
40.94 units on a scale
Standard Deviation 20.85
Knee Injury and Osteoarthritis Outcome Score (KOOS)_Symptoms
6 weeks KOOS Symptoms
64.78 units on a scale
Standard Deviation 16.01
Knee Injury and Osteoarthritis Outcome Score (KOOS)_Symptoms
3 months KOOS Symptoms
71.12 units on a scale
Standard Deviation 18.60
Knee Injury and Osteoarthritis Outcome Score (KOOS)_Symptoms
6 months KOOS Symptoms
75.16 units on a scale
Standard Deviation 18.54
Knee Injury and Osteoarthritis Outcome Score (KOOS)_Symptoms
1 year KOOS Symptoms
83.12 units on a scale
Standard Deviation 15.33
Knee Injury and Osteoarthritis Outcome Score (KOOS)_Symptoms
2 years KOOS Symptoms score
84.49 units on a scale
Standard Deviation 17.07
Knee Injury and Osteoarthritis Outcome Score (KOOS)_Symptoms
5 years KOOS Symptoms
87.90 units on a scale
Standard Deviation 13.13

SECONDARY outcome

Timeframe: Pre-operative to 5 years post-operative

Population: Participants with available data. Participants=knees.

KOOS consists of 5 subscales; Pain, other Symptoms, Function in daily living (ADL), Function in sport and recreation (Sport/Rec) and knee related Quality of life (QOL). The last week is taken into consideration when answering the questions. Standardized answer options are given (5 Likert boxes) and each question gets a score from 0 to 4. A normalized score (100 indicating no symptoms and 0 indicating extreme symptoms) is calculated for each subscale.)

Outcome measures

Outcome measures
Measure
ShapeMatch Cutting Guides With Triathlon
n=100 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Knee Injury and Osteoarthritis Outcome Score (KOOS)_ADL
Pre-op KOOS ADL
38.08 units on a scale
Standard Deviation 20.12
Knee Injury and Osteoarthritis Outcome Score (KOOS)_ADL
6 weeks KOOS ADL
71.98 units on a scale
Standard Deviation 17.58
Knee Injury and Osteoarthritis Outcome Score (KOOS)_ADL
3 months KOOS ADL
78.75 units on a scale
Standard Deviation 18.20
Knee Injury and Osteoarthritis Outcome Score (KOOS)_ADL
6 months KOOS ADL
82.37 units on a scale
Standard Deviation 17.90
Knee Injury and Osteoarthritis Outcome Score (KOOS)_ADL
1 year KOOS ADL
88.14 units on a scale
Standard Deviation 14.39
Knee Injury and Osteoarthritis Outcome Score (KOOS)_ADL
2 years KOOS ADL score
89.60 units on a scale
Standard Deviation 15.46
Knee Injury and Osteoarthritis Outcome Score (KOOS)_ADL
5 years KOOS ADL score
88.80 units on a scale
Standard Deviation 15.09

SECONDARY outcome

Timeframe: Pre-operative to 5 years Post-Operative

Population: Participants with available data. Participants=knees

KOOS consists of 5 subscales; Pain, other Symptoms, Function in daily living (ADL), Function in sport and recreation (Sport/Rec) and knee related Quality of life (QOL). The last week is taken into consideration when answering the questions. Standardized answer options are given (5 Likert boxes) and each question gets a score from 0 to 4. A normalized score (100 indicating no symptoms and 0 indicating extreme symptoms) is calculated for each subscale.)

Outcome measures

Outcome measures
Measure
ShapeMatch Cutting Guides With Triathlon
n=100 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Knee Injury and Osteoarthritis Outcome Score (KOOS)_S&R
Pre-op KOOS S&R
14.45 units on a scale
Standard Deviation 20.98
Knee Injury and Osteoarthritis Outcome Score (KOOS)_S&R
1 year KOOS S&R
65.05 units on a scale
Standard Deviation 25.48
Knee Injury and Osteoarthritis Outcome Score (KOOS)_S&R
2 years KOOS S&R
65.92 units on a scale
Standard Deviation 27.28
Knee Injury and Osteoarthritis Outcome Score (KOOS)_S&R
5 years KOOS S&R
64.78 units on a scale
Standard Deviation 27.00
Knee Injury and Osteoarthritis Outcome Score (KOOS)_S&R
6 weeks KOOS S&R
39.06 units on a scale
Standard Deviation 32.49
Knee Injury and Osteoarthritis Outcome Score (KOOS)_S&R
3 months KOOS S&R
48.58 units on a scale
Standard Deviation 28.74
Knee Injury and Osteoarthritis Outcome Score (KOOS)_S&R
6 months KOOS S&R
58.70 units on a scale
Standard Deviation 29.09

SECONDARY outcome

Timeframe: Pre-operative to 5 years post-operative

Population: Participants with available data. Participants=knees.

KOOS consists of 5 subscales; Pain, other Symptoms, Function in daily living (ADL), Function in sport and recreation (Sport/Rec) and knee related Quality of life (QOL). The last week is taken into consideration when answering the questions. Standardized answer options are given (5 Likert boxes) and each question gets a score from 0 to 4. A normalized score (100 indicating no symptoms and 0 indicating extreme symptoms) is calculated for each subscale.)

Outcome measures

Outcome measures
Measure
ShapeMatch Cutting Guides With Triathlon
n=100 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Knee Injury and Osteoarthritis Outcome Score (KOOS)_QOL
Pre-op KOOS QOL
19.92 unit of a scale
Standard Deviation 17.63
Knee Injury and Osteoarthritis Outcome Score (KOOS)_QOL
6 weeks KOOS QOL score
51.87 unit of a scale
Standard Deviation 22.12
Knee Injury and Osteoarthritis Outcome Score (KOOS)_QOL
3 months KOOS QOL score
61.51 unit of a scale
Standard Deviation 21.14
Knee Injury and Osteoarthritis Outcome Score (KOOS)_QOL
6 months KOOS QOL
69.44 unit of a scale
Standard Deviation 25.39
Knee Injury and Osteoarthritis Outcome Score (KOOS)_QOL
1 year KOOS QOL
77.09 unit of a scale
Standard Deviation 20.78
Knee Injury and Osteoarthritis Outcome Score (KOOS)_QOL
2 years KOOS QOL score
79.82 unit of a scale
Standard Deviation 22.53
Knee Injury and Osteoarthritis Outcome Score (KOOS)_QOL
5 years KOOS QOL
80.19 unit of a scale
Standard Deviation 21.73

SECONDARY outcome

Timeframe: Pre-operative to 5 years Post-Operative

Population: Participants with available data. Participants=knees.

SF-12 provides a summary measure of health status after combining the physical health score (PCS) and mental health score (MCS). The SF-12 Health Survey is a 12 item participant completed questionnaire to measure general health and well-being. It includes a physical and mental status component score: each ranging from 0 to 100 points. Low values represent a poor health state and high values represent a good health state.

Outcome measures

Outcome measures
Measure
ShapeMatch Cutting Guides With Triathlon
n=100 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Short Form Health Survey 12 v2 (SF-12)_Physical Component Summary (PCS)
SF12 PCS Preop
34.36 units on a scale
Standard Deviation 7.69
Short Form Health Survey 12 v2 (SF-12)_Physical Component Summary (PCS)
SF12 PCS 6 weeks
40.27 units on a scale
Standard Deviation 6.98
Short Form Health Survey 12 v2 (SF-12)_Physical Component Summary (PCS)
SF12 PCS 3 months
45.99 units on a scale
Standard Deviation 8.09
Short Form Health Survey 12 v2 (SF-12)_Physical Component Summary (PCS)
SF12 PCS 6 months
47.35 units on a scale
Standard Deviation 8.89
Short Form Health Survey 12 v2 (SF-12)_Physical Component Summary (PCS)
SF12 PCS 1 year
48.27 units on a scale
Standard Deviation 8.88
Short Form Health Survey 12 v2 (SF-12)_Physical Component Summary (PCS)
SF12 PCS 2 years
49.90 units on a scale
Standard Deviation 8.64
Short Form Health Survey 12 v2 (SF-12)_Physical Component Summary (PCS)
SF12 PCS 5 years
46.96 units on a scale
Standard Deviation 8.66

SECONDARY outcome

Timeframe: Pre-Operative to 5 years Post-Operative

Population: Participants with available data. Participants=knees.

Pain at rest and pain during mobilization was measured using a 10 centimeter Visual analogue scale (VAS). Participants are asked to indicate their level of pain with 0 being no pain and 10 being the worst pain.

Outcome measures

Outcome measures
Measure
ShapeMatch Cutting Guides With Triathlon
n=100 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
VAS Pain at Rest
VAS pain at rest_Preop
5.78 centimeters
Standard Deviation 2.49
VAS Pain at Rest
VAS pain at rest_6 weeks
3.09 centimeters
Standard Deviation 2.56
VAS Pain at Rest
VAS pain at rest_3 months
2.02 centimeters
Standard Deviation 2.14
VAS Pain at Rest
VAS pain at rest_6 months
1.45 centimeters
Standard Deviation 1.98
VAS Pain at Rest
VAS pain at rest_ 1 year
1.22 centimeters
Standard Deviation 1.84
VAS Pain at Rest
VAS pain at rest_ 2 years
1.09 centimeters
Standard Deviation 1.82
VAS Pain at Rest
VAS pain at rest_ 5 years
1.04 centimeters
Standard Deviation 1.65

SECONDARY outcome

Timeframe: Pre-Operative to 5 years post-operative

Population: Participants with available data. Participants=knees.

Pain at rest and pain during mobilization was measured using a 10 centimeter Visual analogue scale (VAS). Participants are asked to indicate their level of pain with 0 being no pain and 10 being the worst pain.

Outcome measures

Outcome measures
Measure
ShapeMatch Cutting Guides With Triathlon
n=100 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
VAS Pain Mobilised
VAS pain during mobilization_Preop
7.28 units of a scale
Standard Deviation 2.07
VAS Pain Mobilised
VAS pain during mobilization_6 weeks
3.47 units of a scale
Standard Deviation 2.74
VAS Pain Mobilised
VAS pain during mobilization_3 months
2.39 units of a scale
Standard Deviation 2.48
VAS Pain Mobilised
VAS pain during mobilization_6 months
1.83 units of a scale
Standard Deviation 2.23
VAS Pain Mobilised
VAS pain during mobilization_1 year
1.43 units of a scale
Standard Deviation 1.99
VAS Pain Mobilised
VAS pain during mobilization_2 years
1.41 units of a scale
Standard Deviation 2.19
VAS Pain Mobilised
VAS pain during mobilization_5 years
1.22 units of a scale
Standard Deviation 1.92

SECONDARY outcome

Timeframe: Pre-operative to 5 years Post-Operative

Population: Participants with available data. Participants=knees.

SF-12 provides a summary measure of health status after combining the physical health score (PCS) and mental health score (MCS). The SF-12 Health Survey is a 12 item participant completed questionnaire to measure general health and well-being. It includes a physical and mental status component score: each ranging from 0 to 100 points. Low values represent a poor health state and high values represent a good health state.

Outcome measures

Outcome measures
Measure
ShapeMatch Cutting Guides With Triathlon
n=100 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Short Form Health Survey 12 (SF-12)_Mental Component Summary (MCS)
SF12 MCS Preop
47.02 units on a scale
Standard Deviation 12.49
Short Form Health Survey 12 (SF-12)_Mental Component Summary (MCS)
SF12 MCS 6 weeks
49.91 units on a scale
Standard Deviation 10.56
Short Form Health Survey 12 (SF-12)_Mental Component Summary (MCS)
SF12 MCS 3 months
52.18 units on a scale
Standard Deviation 9.96
Short Form Health Survey 12 (SF-12)_Mental Component Summary (MCS)
SF12 MCS 6 months
52.58 units on a scale
Standard Deviation 9.15
Short Form Health Survey 12 (SF-12)_Mental Component Summary (MCS)
SF12 MCS 1 year
52.93 units on a scale
Standard Deviation 9.28
Short Form Health Survey 12 (SF-12)_Mental Component Summary (MCS)
SF12 MCS 2 years
52.78 units on a scale
Standard Deviation 9.27
Short Form Health Survey 12 (SF-12)_Mental Component Summary (MCS)
SF12 MCS 5 years
52.95 units on a scale
Standard Deviation 10.39

SECONDARY outcome

Timeframe: Pre-operative to 5 years Post-Operative

Population: Participants with available data. Participants=knees.

The Knee Society Clinical Rating System is comprised of two distinct sub-scores: one for pain, range of motion (ROM) and joint stability, and one for functional parameters. Sub-scores range from a minimum score of 0 to a maximum of 100 points. Although the specific scores are not distinguished as "excellent," "good," "fair," or "poor," a higher value represents a better outcome.

Outcome measures

Outcome measures
Measure
ShapeMatch Cutting Guides With Triathlon
n=100 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Knee Society Clinical Rating System (KSS) Pain Scores
KSS Pain Preop
32.95 units on a scale
Standard Deviation 14.06
Knee Society Clinical Rating System (KSS) Pain Scores
KSS Pain 3 months
69.05 units on a scale
Standard Deviation 18.46
Knee Society Clinical Rating System (KSS) Pain Scores
KSS Pain 6 months
71.36 units on a scale
Standard Deviation 15.21
Knee Society Clinical Rating System (KSS) Pain Scores
KSS Pain 1 year
76.75 units on a scale
Standard Deviation 16.53
Knee Society Clinical Rating System (KSS) Pain Scores
KSS Pain 2 years
78.04 units on a scale
Standard Deviation 16.32
Knee Society Clinical Rating System (KSS) Pain Scores
KSS Pain 5 years
75.60 units on a scale
Standard Deviation 13.96

SECONDARY outcome

Timeframe: Pre-operative to 5 years Post-Operative

Population: Participants with available data. Participants=knees.

The Knee Society Clinical Rating System is comprised of two distinct sub-scores: one for pain, range of motion (ROM) and joint stability, and one for functional parameters. Sub-scores range from a minimum score of 0 to a maximum of 100 points. Although the specific scores are not distinguished as "excellent," "good," "fair," or "poor," a higher value represents a better outcome.

Outcome measures

Outcome measures
Measure
ShapeMatch Cutting Guides With Triathlon
n=100 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Knee Society Clinical Rating System (KSS) Functional Scores
KSS functional Preop
43.45 units on a scale
Standard Deviation 19.25
Knee Society Clinical Rating System (KSS) Functional Scores
KSS functional 3 months
66.82 units on a scale
Standard Deviation 20.07
Knee Society Clinical Rating System (KSS) Functional Scores
KSS functional 6 months
75.45 units on a scale
Standard Deviation 20.28
Knee Society Clinical Rating System (KSS) Functional Scores
KSS functional 1 year
76.99 units on a scale
Standard Deviation 19.79
Knee Society Clinical Rating System (KSS) Functional Scores
KSS functional 2 years
74.82 units on a scale
Standard Deviation 23.62
Knee Society Clinical Rating System (KSS) Functional Scores
KSS functional 5 years
71.44 units on a scale
Standard Deviation 25.47

SECONDARY outcome

Timeframe: Pre-operative to 5 years Post-Operative

Population: Participants with available data. Participants=knees.

The Knee Society Clinical Rating System is comprised of two distinct sub-scores: one for pain, range of motion (ROM) and joint stability, and one for functional parameters. Sub-scores range from a minimum score of 0 to a maximum of 100 points. Although the specific scores are not distinguished as "excellent," "good," "fair," or "poor," a higher value represents a better outcome.

Outcome measures

Outcome measures
Measure
ShapeMatch Cutting Guides With Triathlon
n=100 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Knee Society Clinical Rating System (KSS) Range of Motion Scores
KSS ROM Preop
108.59 units on a scale
Standard Deviation 16.74
Knee Society Clinical Rating System (KSS) Range of Motion Scores
KSS ROM 3 months
110.40 units on a scale
Standard Deviation 14.38
Knee Society Clinical Rating System (KSS) Range of Motion Scores
KSS ROM 6 months
112.71 units on a scale
Standard Deviation 12.71
Knee Society Clinical Rating System (KSS) Range of Motion Scores
KSS ROM 1 year
115.30 units on a scale
Standard Deviation 12.36
Knee Society Clinical Rating System (KSS) Range of Motion Scores
KSS ROM 2 years
115.09 units on a scale
Standard Deviation 12.40
Knee Society Clinical Rating System (KSS) Range of Motion Scores
KSS ROM 5 years
119.11 units on a scale
Standard Deviation 13.06

SECONDARY outcome

Timeframe: 1 to 5 years Post-Operative

Population: Participants with available data. Participants=knees.

The Forgotten Joint Score is a newly-developed twelve-item, self-reported assessment of how aware recipients of hip and knee joint replacement are of their joint in everyday life. The total score for the FJS is summed, averaged then multiplied by 25 (never = 0 points; almost never = 1 point; seldom = 2 points; sometimes = 3 points; mostly = 4 points). Total score range of 0 to 100.

Outcome measures

Outcome measures
Measure
ShapeMatch Cutting Guides With Triathlon
n=100 Participants
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Forgotten Joint Score (FJS)
FJS 1 year
54.48 units on a scale
Standard Deviation 30.58
Forgotten Joint Score (FJS)
FJS 2 years
40.28 units on a scale
Standard Deviation 30.08
Forgotten Joint Score (FJS)
FJS 5 years
68.82 units on a scale
Standard Deviation 31.17

Adverse Events

ShapeMatch Cutting Guides With Triathlon

Serious events: 48 serious events
Other events: 47 other events
Deaths: 1 deaths

Serious adverse events

Serious adverse events
Measure
ShapeMatch Cutting Guides With Triathlon
n=96 participants at risk
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
Blood and lymphatic system disorders
Non-Operative site
2.1%
2/96 • Number of events 15 • 5 years
Cardiac disorders
Non-operative site
5.2%
5/96 • Number of events 6 • 5 years
Ear and labyrinth disorders
Non-operative site
2.1%
2/96 • Number of events 2 • 5 years
Eye disorders
Non-operative site
5.2%
5/96 • Number of events 5 • 5 years
Gastrointestinal disorders
Non-operative site
2.1%
2/96 • Number of events 2 • 5 years
General disorders
Non-operative site
3.1%
3/96 • Number of events 3 • 5 years
Hepatobiliary disorders
Non-operative site
1.0%
1/96 • Number of events 1 • 5 years
Infections and infestations
Non-operative site
1.0%
1/96 • Number of events 1 • 5 years
Infections and infestations
Operative site
2.1%
2/96 • Number of events 4 • 5 years
Injury, poisoning and procedural complications
Non-Operative site
2.1%
2/96 • Number of events 2 • 5 years
Injury, poisoning and procedural complications
Operative Site
4.2%
4/96 • Number of events 4 • 5 years
Metabolism and nutrition disorders
Non-operative site
1.0%
1/96 • Number of events 1 • 5 years
Musculoskeletal and connective tissue disorders
Non-operative site
29.2%
28/96 • Number of events 38 • 5 years
Musculoskeletal and connective tissue disorders
Operative site
8.3%
8/96 • Number of events 8 • 5 years
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Non-operative site
5.2%
5/96 • Number of events 11 • 5 years
Psychiatric disorders
Non-operative site
1.0%
1/96 • Number of events 1 • 5 years
Renal and urinary disorders
Non-operative site
5.2%
5/96 • Number of events 5 • 5 years
Reproductive system and breast disorders
Non-operative site
2.1%
2/96 • Number of events 2 • 5 years
Respiratory, thoracic and mediastinal disorders
Non-operative site
7.3%
7/96 • Number of events 9 • 5 years
Skin and subcutaneous tissue disorders
Non-operative site
3.1%
3/96 • Number of events 3 • 5 years
Skin and subcutaneous tissue disorders
Operative site
1.0%
1/96 • Number of events 1 • 5 years
Surgical and medical procedures
Non-operative site
22.9%
22/96 • Number of events 38 • 5 years
Surgical and medical procedures
Operative site
6.2%
6/96 • Number of events 6 • 5 years
Vascular disorders
Non-operative side
4.2%
4/96 • Number of events 4 • 5 years

Other adverse events

Other adverse events
Measure
ShapeMatch Cutting Guides With Triathlon
n=96 participants at risk
Participants who underwent Total Knee Replacement (TKR) with the Stryker Triathlon® Total Knee System using the ShapeMatch® Cutting Guides.
General disorders
Non-operative site
8.3%
8/96 • Number of events 10 • 5 years
Musculoskeletal and connective tissue disorders
Non-operative site
21.9%
21/96 • Number of events 32 • 5 years
Musculoskeletal and connective tissue disorders
Operative site
5.2%
5/96 • Number of events 9 • 5 years
Respiratory, thoracic and mediastinal disorders
Non-operative site
8.3%
8/96 • Number of events 10 • 5 years
Skin and subcutaneous tissue disorders
Non-operative site
5.2%
5/96 • Number of events 6 • 5 years

Additional Information

David Fulker

Stryker SP

Phone: +61 2 9467 1072

Results disclosure agreements

  • Principal investigator is a sponsor employee Discloser must give at least 40 days notice to Sponsor including a copy of the proposed publication. The Sponsor can then provide comments (which Discloser is not bound to follow), request delay of publication by no more than 120 days to allow for Sponsor to protect its intellectual property, or request that the Discloser remove certain proprietary or confidential information from the study (other than the results of the study).
  • Publication restrictions are in place

Restriction type: OTHER