Post-market Safety Reassessment of Ulinastatin for Injection

NCT ID: NCT02520570

Last Updated: 2018-04-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-08-31

Study Completion Date

2018-08-31

Brief Summary

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1. Investigate the application of ulinastatin(UTI) in real practice clinic.(eg:population character, usage and dosage, course of treatment,etc )
2. Analysis the incidence of adverse drug reactions /adverse events of ulinastatin, collect the main clinical manifestations, treatment, outcome, influence factors; provide evidence for improving the recommended medication plan of ulinastatin.
3. Evaluate the safety of ulinastatin , obtain scientific conclusion , and provide evidence for appropriate medication to administration department of health authority.

Detailed Description

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In order to find out the application of ulinastatin in real practice clinic , identify the high risk group for adverse event/adverse drug reaction and calculate the adverse event/adverse drug reaction incidence rate, a large sample size clinical trial has been designed. This trial is an observational study. The investigators would screen several hospitals from different provinces and prospectively collect the main clinical manifestations,treatment, outcome, influence factors about patients using ulinastatin either in general clinical departments or in ICU. This study would be expected to provide evidence for appropriate medication to administration department of health authority.

Conditions

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Adverse Reaction to Drug

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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general department

Patients using ulinastatin in department beyond ICU would be labelled as general department group.

ulinastatin

Intervention Type DRUG

We wouldn't intervene the doctors how to treat with the patients or how to use the drug, we just observe the react of patients after treated with ulinastatin.

ICU

Patients using ulinastatin in ICU would be labelled as ICU group.

ulinastatin

Intervention Type DRUG

We wouldn't intervene the doctors how to treat with the patients or how to use the drug, we just observe the react of patients after treated with ulinastatin.

Interventions

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ulinastatin

We wouldn't intervene the doctors how to treat with the patients or how to use the drug, we just observe the react of patients after treated with ulinastatin.

Intervention Type DRUG

Other Intervention Names

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UTI urinary trypsin inhibitor bikunin

Eligibility Criteria

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Inclusion Criteria

* Patients with ulinastatin treated

Exclusion Criteria

* Not applicable
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Center for ADR Monitoring of Guangdong

UNKNOWN

Sponsor Role collaborator

Techpool Bio-Pharma Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jin Li, doctor

Role: PRINCIPAL_INVESTIGATOR

Center for Adverse Drug Reaction Monitoring of Guangdong

Locations

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Guangdong Provincial Hospital of Traditional Chinese Medicine

Guangzhou, Guangdong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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mingjuan Hua, Master

Role: CONTACT

+86 020 38972288

Facility Contacts

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Hua Lin

Role: primary

86-020-81887233

Other Identifiers

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002/20140709

Identifier Type: -

Identifier Source: org_study_id

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