Treatment of Periodontal Intrabony Defects Using Autologous Platelet Rich Fibrin vs Titanium Platelet Rich Fibrin
NCT ID: NCT02512952
Last Updated: 2015-07-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2/PHASE3
38 participants
INTERVENTIONAL
2014-06-30
2015-03-31
Brief Summary
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Materials and methods: Study was conducted on subjects reporting to the Department of Periodontics, The Oxford Dental College and Hospital, Bangalore. 38 subjects with 90 periodontal IBDs of moderate to severe periodontitis were selected and assigned to OFD alone (group I) or OFD with Autologous PRF (group II) or OFD with TPRF (group III). In each subject, a minimum number of two sextants were present with probing pocket depths (PPD) ≥5mm in at least three teeth.
Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Group 1
SRP with Open flap debridement (OFD) alone for treating periodontal pocket
Open flap debridement (OFD)
Oral prophylaxis followed by Open flap debridement (OFD)
Group 2
SRP with Open flap debridement (OFD) with Platelet rich fibrin (PRF) placement into bone defect
OFD with Platelet rich fibrin (PRF)
Oral prophylaxis followed by Open flap debridement (OFD) with Platelet rich fibrin (PRF) placement into the bone defect
Group 3
SRP with Open flap debridement (OFD) with Titanium Platelet rich fibrin (TPRF) placement into bone defect
OFD with Titanium Platelet rich fibrin (TPRF)
Oral prophylaxis followed by Open flap debridement (OFD) with Titanium Platelet rich fibrin (TPRF) placement into the bone defect
Interventions
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Open flap debridement (OFD)
Oral prophylaxis followed by Open flap debridement (OFD)
OFD with Platelet rich fibrin (PRF)
Oral prophylaxis followed by Open flap debridement (OFD) with Platelet rich fibrin (PRF) placement into the bone defect
OFD with Titanium Platelet rich fibrin (TPRF)
Oral prophylaxis followed by Open flap debridement (OFD) with Titanium Platelet rich fibrin (TPRF) placement into the bone defect
Eligibility Criteria
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Inclusion Criteria
* age group 20-55 years
* radiographic evidence of periodontal IBDs
* probing pocket depth (PPD) \>5mm in minimum two sextants in at least three teeth
* clinical attachment (CA) loss of ≥ 3mm.
Exclusion Criteria
* those on medications (corticosteroids/ bisphosphonate therapy) that may interfere with wound healing
* grade III tooth mobility
* smokers and alcoholic subjects
* pregnant and lactating mothers
* subjects who underwent periodontal treatment within a period of 1 year.
20 Years
55 Years
ALL
No
Sponsors
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The Oxford Dental College, Hospital and Research Center, Bangalore, India
OTHER
Government Dental College and Research Institute, Bangalore
OTHER
Responsible Party
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Dr. A R Pradeep
Professor and Head
Locations
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Government Dental College and Research Institute
Bangalore, Karnataka, India
The Oxford Dental College
Bangalore, Karnataka, India
Countries
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Other Identifiers
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224/2013-14
Identifier Type: -
Identifier Source: org_study_id