Usefulness of Non-invasive Radiofrequency Therapy for Facial Contouring

NCT ID: NCT02512822

Last Updated: 2015-07-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

21 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-11-30

Study Completion Date

2015-07-31

Brief Summary

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To evaluate the efficacy of novel noninvasive RF technology for reduction of submental fat.

Detailed Description

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Recently, Novel radiofrequency (RF) technology was introduced as a promising tool for non-invasive body and face contouring, which can heats subcutaneous fat up to 45℃ continuously without surface damage and induces adipocytes apoptosis.

Subjects with an excessive subcutaneous fat on the submental area received twice treatments at 1-month intervals. Clinical outcomes including the thickness of the submental fat (measured by ultrasound) and the submental circumference (measured by a tape measure), and clinical photographs were obtained at baseline, and 1-month and 6-month after last treatment.

Conditions

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Subcutaneous Fat

Keywords

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radiofrequency submental fat fat reduction body contouring

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Participants

Noninvasive Radiofrequency

Group Type EXPERIMENTAL

Noninvasive Radiofrequency TruSculpt

Intervention Type PROCEDURE

Heating subcutaneous fat up to 45℃ continuously at least 3 minutes without surface damage and induces adipocytes apoptosis.

Interventions

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Noninvasive Radiofrequency TruSculpt

Heating subcutaneous fat up to 45℃ continuously at least 3 minutes without surface damage and induces adipocytes apoptosis.

Intervention Type PROCEDURE

Other Intervention Names

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TruSculpt

Eligibility Criteria

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Inclusion Criteria

* clinically appreciable localized excess of subcutaneous fat on the submental area
* no history of systemic underlying disease

Exclusion Criteria

* any infectious or inflammatory skin diseases
* keloids
* psychiatric patients
* systemic underlying disease
* who had taken aesthetic procedure on the face, before 6-month

* more than 5% weight change were dropped out.
Minimum Eligible Age

20 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cutera Inc.

INDUSTRY

Sponsor Role collaborator

Kangbuk Samsung Hospital

OTHER

Sponsor Role lead

Responsible Party

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Won-Serk Kim

Associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Won-Serk Kim, M.D., Ph.D.

Role: STUDY_DIRECTOR

Kangbuk Samsung Hospital

References

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Franco W, Kothare A, Ronan SJ, Grekin RC, McCalmont TH. Hyperthermic injury to adipocyte cells by selective heating of subcutaneous fat with a novel radiofrequency device: feasibility studies. Lasers Surg Med. 2010 Jul;42(5):361-70. doi: 10.1002/lsm.20925.

Reference Type BACKGROUND
PMID: 20583242 (View on PubMed)

Franco W, Kothare A, Goldberg DJ. Controlled volumetric heating of subcutaneous adipose tissue using a novel radiofrequency technology. Lasers Surg Med. 2009 Dec;41(10):745-50. doi: 10.1002/lsm.20876.

Reference Type BACKGROUND
PMID: 20014265 (View on PubMed)

Other Identifiers

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KBC13251D

Identifier Type: -

Identifier Source: org_study_id