Trial Outcomes & Findings for Albuterol to Improve Respiratory Strength in SCI (NCT NCT02508311)

NCT ID: NCT02508311

Last Updated: 2024-05-07

Results Overview

Respiratory muscle strength will be determined by maximal inspiratory pressure and maximal expiratory pressure at the mouth during baseline visit, week 16 visit and week 18 visit.

Recruitment status

TERMINATED

Study phase

PHASE4

Target enrollment

1 participants

Primary outcome timeframe

Baseline, Week 16, Week 18

Results posted on

2024-05-07

Participant Flow

Several participants failed screening, and thus were not randomized to either the treatment or placebo arm.

Participant milestones

Participant milestones
Measure
Active Oral Beta-2
Subjects will receive 16 weeks of active medication. Oral Albuterol Extended Release: Subjects will receive extended release Albuterol, 4mg twice daily for the first week. The remaining 15 weeks subjects will receive extended release Albuterol, 8mg twice daily.
Placebo
Subjects will receive 16 weeks of placebo medication. Placebo: Subjects will receive placebo tablets twice daily for 16 weeks.
Overall Study
STARTED
1
0
Overall Study
COMPLETED
0
0
Overall Study
NOT COMPLETED
1
0

Reasons for withdrawal

Reasons for withdrawal
Measure
Active Oral Beta-2
Subjects will receive 16 weeks of active medication. Oral Albuterol Extended Release: Subjects will receive extended release Albuterol, 4mg twice daily for the first week. The remaining 15 weeks subjects will receive extended release Albuterol, 8mg twice daily.
Placebo
Subjects will receive 16 weeks of placebo medication. Placebo: Subjects will receive placebo tablets twice daily for 16 weeks.
Overall Study
Withdrawal by Subject
1
0

Baseline Characteristics

Albuterol to Improve Respiratory Strength in SCI

Baseline characteristics by cohort

Baseline data not reported

PRIMARY outcome

Timeframe: Baseline, Week 16, Week 18

Population: 1 participant screened and qualifies; however the participant dropped out. No data on this participant was collected.

Respiratory muscle strength will be determined by maximal inspiratory pressure and maximal expiratory pressure at the mouth during baseline visit, week 16 visit and week 18 visit.

Outcome measures

Outcome data not reported

Adverse Events

Active Oral Beta-2

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Placebo

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Gregory Schilero

James J Peters VA Medical Center

Phone: 7185849000

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place