SYNERGY China: Assess SYNERGY Stent in China

NCT ID: NCT02499692

Last Updated: 2020-09-16

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

103 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-05-31

Study Completion Date

2017-08-31

Brief Summary

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Prospective, multicenter, single-arm study, enroll 100 patients in no more than 10 sites across China, the primary endpoint is Technical success.

Detailed Description

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The study is To evaluate clinical and peri-procedural angiographic outcomes for the SYNERGYTM MONORAILTM Everolimus-Eluting Platinum Chromium Coronary Stent System in the treatment of subjects with atherosclerotic lesion(s) ≤34 mm in length (by visual estimate) in native coronary arteries ≥2.25 mm to ≤4.0 mm in diameter (by visual estimate).

Conditions

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Cardiovascular Diseases

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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SYNERGYTM Coronary Stent System

Device:SYNERGY MONORAIL Everolimus-Eluting Platinum Chromium Coronary Stent System

Group Type EXPERIMENTAL

SYNERGYTM Coronary Stent System

Intervention Type DEVICE

SYNERGYTM MONORAILTM Everolimus-Eluting Platinum Chromium Coronary Stent System

Interventions

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SYNERGYTM Coronary Stent System

SYNERGYTM MONORAILTM Everolimus-Eluting Platinum Chromium Coronary Stent System

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Subject must be at least 18 -75 years of age
2. Subject is eligible for percutaneous coronary intervention (PCI)
3. Target lesion(s) must be located in a native coronary artery with a visually estimated reference vessel diameter (RVD) ≥2.25 mm and ≤4.0 mm, length must be ≤34\* mm (by visual estimate), Target lesion(s) must have visually estimated stenosis ≥50% and \<100% with thrombolysis in Myocardial Infarction (TIMI) flow \>1

Exclusion Criteria

1. Planned PCI (including staged procedures) or CABG after the index procedure
2. Subject with out of range complete blood count (CBC) values that are determined by the study physician to be clinically significant.
3. Subject is on dialysis or has baseline serum creatinine level \>2.0 mg/dL (177µmol/L)
4. Planned treatment of more than 3 lesions, Planned treatment of lesions in more than 2 major epicardial vessels, Planned treatment of a single lesion with more than 1 stent
5. Target lesion(s) is located within 3 mm of the origin of the left anterior descending (LAD) coronary artery or left circumflex (LCx) coronary artery by visual estimate.
6. Target vessel develops a dissection greater than National Heart, Lung, Blood Institute (NHLBI) type C following the pre-dilatation/pre-treatment of the first target lesion
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Boston Scientific Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Yalin Han

Role: PRINCIPAL_INVESTIGATOR

Shenyang Northern Hospital (The General Hospital of Shenyang Military Region)

Locations

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AeroSpace center hospital

Beijing, , China

Site Status

the second hospital of Jilin Unversity

Changcun, , China

Site Status

Daqing General Oil Field Hospital

Daqing, , China

Site Status

Sir Run Run Shaw Hospital of Zhejiang University School of Medicine

Hangzhou, , China

Site Status

The First Hospital of Lanzhou University

Lanzhou, , China

Site Status

General Hospital of SY Military Institute

Shenyang, , China

Site Status

TEDA International Cardiovascular Hospital

Tianjin, , China

Site Status

Wuhan Asia Heart Hospital

Wuhan, , China

Site Status

Countries

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China

Other Identifiers

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S2342

Identifier Type: -

Identifier Source: org_study_id

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