Post-transplant Cancer Incidence and Survival in Patients With or Without Pre-transplant Cancer

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2370 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-10-31

Study Completion Date

2015-06-30

Brief Summary

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Patients with previous malignancies have increasingly been accepted for renal transplantation. However, post-transplant malignancy risk and survival rates of these patients are unknown. Our aim was to assess if previous malignancies pose an unnecessarily high risk of post-transplant malignant tumours and if the organs as a resource are too limited for investment in this patient group.

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Detailed Description

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Conditions

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Neoplasms Kidney Failure

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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KTx Uppsala

Patients who have received a kidney transplant in Uppsala.

No interventions assigned to this group

KTx Europe

Patients who have received a kidney transplant in Uppsala.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Kidney transplanted patients from January 1982 through December 2013 with or without a pre transplant cancer.

Exclusion Criteria

* Simultaneous kidney+pancreas transplantation.
* Islet cell transplanted patients
* Undiagnosed malignancies at the time of transplantation
* Death within a week after transplantation
* First transplantation at another hospital

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No