Feasibility of a Consumer Based Accelerometer in Monitoring Outpatient Physical Activity: A Study in Patients With Cancer and Amyotrophic Lateral Sclerosis

NCT ID: NCT02457715

Last Updated: 2017-12-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-07-31

Study Completion Date

2017-10-31

Brief Summary

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This is a parallel group, single institution, prospective clinical study. The purpose of this study is to assess whether the Jawbone Up 24, a consumer based accelerometer, can be a feasible tool to study physical activity in cancer patients and patients with Amyotrophic Lateral Sclerosis (ALS).

Detailed Description

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Conditions

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Prostate Cancer Renal Cancer Brain Cancer ALS

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Prostate Cancer

Subjects will use a Jawbone Up24 for 14 weeks.

No interventions assigned to this group

Renal Cancer

Subjects will use a Jawbone Up24 for 14 weeks.

No interventions assigned to this group

Brain Cancer

Subjects will use a Jawbone Up24 for 14 weeks.

No interventions assigned to this group

Amyotrophic Lateral Sclerosis (ALS)

Subjects will use a Jawbone Up24 for 14 weeks.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients \> = 18 years of age.
* Patient must be able to ambulate and complete the 6 minute walk test without use of a walker, cane, or any assist devices.
* Cancer patients or ALS patients who meet the following criteria:

Prostate cancer:

* Histologically confirmed prostate cancer.
* Patients who are initiating any chemotherarpy (examples are docetaxel, cabazitaxel, etc.) and/or hormone directed treatment for prostate cancer. Examples of hormone directed therapy include GnRH agonist or antagonists (such as leuprolide, goserelin, triptorelin, histrelin and degarelix), androgen receptor blockers (such as bicalutamide or enzalutamide), or androgen biosynthesis inhibitors (such as abiraterone).

Renal cancer:

* Histologically confirmed renal cell carcinoma (RCC).
* Metastatic disease, in the opinion of the treating provider.
* Starting any systemic therapy for metastatic disease

Brain cancer:

* Histologically confirmed high grade glioma.
* Status post concurrent radiation therapy and daily temozolomide.
* Starting adjuvant temozolomide therapy.

ALS patients who are:

* Already on a stable dose of Riluzole for at least one month.
* ALSFRS-R with \<or equal to 2 point decline in last month.
* Must have ALSFRS-R walking score of at least 3 or 4 and FVC at least 50% (to ensure patients are fit enough for ambulation and physical activity).

\- Technology requirement:
* Patients will need to own a smart phone that can interface with the Jawbone Up 24.
* Patients willing to provide their own internet access for this study. This will include either a data plan or Wi-Fi access on the patient's smart phone for use of the Jawbone App. They will also need internet access (through their smart phone or home computer) for setting up a SGHIx account. Patients are welcome to use the free guest Wi-Fi access within the Duke Outpatient clinic area for the purpose of this study.
* Patients will need a home computer or adaptor with USB port to charge the Jawbone Up 24.

Exclusion Criteria

* Non-English Speaking or inability to read and understand English
* Presence of cardiovascular disease that would make physical activity risky at the discretion of the provider.
* Any patient who is unable to comprehend and operate the activity tracker at the discretion of the enrolling provider.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Duke University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michael Harrison, MD

Role: PRINCIPAL_INVESTIGATOR

Duke University

Locations

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Duke University Medical Center

Durham, North Carolina, United States

Site Status

Countries

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United States

Other Identifiers

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Pro00063108

Identifier Type: -

Identifier Source: org_study_id