Magnet Resonance Imaging to Evaluate of Dynamic T2 Preparation Puls by Patients With Shunt or Chronic Obstructive Pulmonary Disease

NCT ID: NCT02449083

Last Updated: 2015-11-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-06-30

Study Completion Date

2015-08-31

Brief Summary

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There is preliminary evidence that a dynamic T2 Preparations Puls sequence by cardiac magnet resonance imaging can differentiate between oxygenated and deoxygenated blood.

In adult patients with inborn heart defects this has not yet been researched. Therefore,patients with ventriculoperitoneal shunt, septal and atrio-septal shunt should be examined. Also, patients with chronic obstructive pulmonary disease should be examined.

The aim of this study is the validation of a novel magnet resonance sequence in terms of a distinction of oxygenated blood to deoxygenated blood in comparison to invasive method of measuring cardiac catheterization.

Detailed Description

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Conditions

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Dynamic T2 Preparation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Arm 1

Patients with indication for MRI and coronary angiography

MRI

Intervention Type PROCEDURE

MRI

coronary angiography

Intervention Type PROCEDURE

coronary angiography

Arm 2

Patients with atrioseptal or ventriculoseptal Shunt with indication to coronary angiography

MRI

Intervention Type PROCEDURE

MRI

coronary angiography

Intervention Type PROCEDURE

coronary angiography

Arm 3

Patients with chronic obstructive pulmonary disease with indication to coronary angiography

MRI

Intervention Type PROCEDURE

MRI

coronary angiography

Intervention Type PROCEDURE

coronary angiography

Interventions

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MRI

MRI

Intervention Type PROCEDURE

coronary angiography

coronary angiography

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patients with atrial septal defect (ASD) or ventricular septal defect (VSD) and COPD
* written informed consent

Exclusion Criteria

* patients with ST-elevation
* contraindication for MRI
* heavy kidney disease
* pregnant or breast feeding women
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Heinrich-Heine University, Duesseldorf

OTHER

Sponsor Role lead

Responsible Party

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Klinik für Kardiologie, Pneumologie und Angiologie

Dr. med. Britta Butzbach

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Britta Butzbach, MD

Role: PRINCIPAL_INVESTIGATOR

Heinrich-Heine University, Duesseldorf

Locations

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University Hospital Duesseldorf

Düsseldorf, , Germany

Site Status

Countries

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Germany

Other Identifiers

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13-007

Identifier Type: -

Identifier Source: org_study_id