Interest of the F18-choline as a Second Line of the Tracer for Detection of Parathyroid Adenomas

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-03-31

Study Completion Date

2017-02-28

Brief Summary

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The rationale for the proposed pilot study is to investigate the ability of PET-CT with F18-choline to detect and locate the parathyroid adenoma in patients with primary hyperparathyroidism and negative or non-contributory MIBI (Tc-99m sestamibi) and cervical ultrasound, in order to avoid unnecessary bilateral cervical exploration.

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Detailed Description

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Conditions

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Hyperparathyroidism

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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F18-choline PET

F18-choline PET examination will be performed before surgery

Group Type EXPERIMENTAL

F18-choline PET examination

Intervention Type RADIATION

F18-choline PET examination will be performed before surgery

Interventions

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F18-choline PET examination

F18-choline PET examination will be performed before surgery

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Patient aged 18 years or more;
* Patient with a primary hyperparathyroidism and witj a negative or non-contriburatory MIBI parathyroid scintigraphy and neck ultrasonography, for which surgical resection is planned;
* Confirmation of the diagnosis of primary hyperparathyroidism on laboratory tests
* Affiliate to a social security system;
* Patient written informed consent.

Exclusion Criteria

* Patient deprived of liberty, under guardianship;
* Any medical or psychological condition witch could compromise the capacity of the patient to participate in the study;
* Pregnant or breastfeeding

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No