Comparison of Tab.Labetalol and Tab.Nifedipine for Management of Postpartum Hypertension

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE3

Total Enrollment

98 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-05-31

Study Completion Date

2016-12-31

Brief Summary

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To compare effectiveness of oral labetalol and oral nifedipine for management of postpartum hypertension.

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Detailed Description

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A comparison of oral labetalol and oral nifedipine for management of postpartum hypertension. Which drug is more effective in lowering blood pressures in patient with postpartum hypertension.

Conditions

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Postnatal Hypertension

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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group A

tab.labetalol is given to the patient with postpartum hypertension in dose of 100 mg 6 hourly increased to maximum 600 mg in 24 hours

Group Type ACTIVE_COMPARATOR

Labetalol

Intervention Type DRUG

anti-hypertensive agents

group B

tab.nifedipine is given to the patient with postpartum hypertension in the dose of 10 mg twice a day to maximum dose of 60 mg per 24 hours

Group Type ACTIVE_COMPARATOR

Nifedipine

Intervention Type DRUG

calcium channel blocker ,for lowering blood pressure

Interventions

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Labetalol

anti-hypertensive agents

Intervention Type DRUG

Nifedipine

calcium channel blocker ,for lowering blood pressure

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* all women with postpartum hypertension as a continuation of pregnancy induced hypertension,eclampsia, pre-eclampsia or new onset de-novo postpartum hypertension,of any parity.
* age group between 18-48.
* after informed consent.

Exclusion Criteria

* all women with chronic hypertension, uncontrolled and un treated medical disorders will be excluded.
* conditions in which drugs labetalol and nifedipine is contraindicated.

Minimum Eligible Age

20 Years

Maximum Eligible Age

48 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes