High vs Standard Energy Children's Drink Study

NCT ID: NCT02419599

Last Updated: 2017-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

51 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-08-31

Study Completion Date

2016-08-31

Brief Summary

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This study is a pilot trial investigating the effects of a high energy drink for children, in comparison to standard energy drink for children.

Detailed Description

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A four week, multi-centre, randomised controlled trial investigating the effects of a high energy density, low volume oral nutritional supplement versus standard energy density oral nutritional supplements in children aged 1-12yrs old requiring nutritional support. Fifty eligible children will be recruited and randomised to receive either the high energy density oral nutritional supplement or the standard energy density oral nutritional supplement for four weeks. The primary outcome is nutrient intake, with secondary outcomes of compliance, tolerance, acceptability, anthropometry and safety.

Conditions

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Growth Failure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Group A

The group who will receive high energy density, low volume oral nutritional supplement, to be taken for 4 weeks (28 days)

Group Type EXPERIMENTAL

HE ONS

Intervention Type OTHER

High energy density, low volume oral nutritional supplement (HE ONS) in addition to appropriate nutritional management

Group B

The group who will receive the standard energy density oral nutritional supplement, to be taken for 4 weeks (28 days)

Group Type ACTIVE_COMPARATOR

SE ONS

Intervention Type OTHER

Standard energy density oral nutritional supplement (SE ONS) in addition to appropriate nutritional management

Interventions

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HE ONS

High energy density, low volume oral nutritional supplement (HE ONS) in addition to appropriate nutritional management

Intervention Type OTHER

SE ONS

Standard energy density oral nutritional supplement (SE ONS) in addition to appropriate nutritional management

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Male or female
* Aged 1-12yrs
* Faltering growth and/or requiring oral nutritional supplements to meet nutritional requirements
* Expected to receive at least one bottle of the study product per day
* Able to take study products orally during the study period
* Written informed consent from parent/carer

Exclusion Criteria

* Requirement for 100% of their nutrition via enteral tube and/or parenteral feeding.
* Children with major hepatic or renal dysfunction
* Children with galactosaemia or severe lactose intolerance
* Requirement for elemental or semi-elemental feeds
* Investigator concern around willingness/ability of child/parent/carer to comply with protocol requirements
* Participation in other studies within 2 weeks of study
Minimum Eligible Age

1 Year

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Nutricia UK Ltd

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

References

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Hubbard GP, Fry C, Sorensen K, Casewell C, Collins L, Cunjamalay A, Simpson M, Wall A, Van Wyk E, Ward M, Hallowes S, Duggan H, Robison J, Gane H, Pope L, Clark J, Stratton RJ. Energy-dense, low-volume paediatric oral nutritional supplements improve total nutrient intake and increase growth in paediatric patients requiring nutritional support: results of a randomised controlled pilot trial. Eur J Pediatr. 2020 Sep;179(9):1421-1430. doi: 10.1007/s00431-020-03620-9. Epub 2020 Mar 13.

Reference Type DERIVED
PMID: 32170451 (View on PubMed)

Other Identifiers

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FC125

Identifier Type: -

Identifier Source: org_study_id