Clinical Trial to Evaluate the Efficacy and Safety of 'URSA SOFT CAP. (UDCA-003)' in Fatigue Patients With Liver Dysfunction

NCT ID: NCT02415777

Last Updated: 2016-01-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

168 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-10-31

Study Completion Date

2015-07-31

Brief Summary

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A multi-center, randomized, double-blind, placebo-controlled trial to evaluate the efficacy and safety of 'URSA SOFT CAP. (UDCA-003)' in fatigue patients with liver dysfunction

Detailed Description

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Conditions

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Fatigue

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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udca003

udca003

Group Type EXPERIMENTAL

Ursodeoxycholic acid, thiamine, riboflavin

Intervention Type DRUG

placebo

placebo of udca003

Group Type PLACEBO_COMPARATOR

Ursodeoxycholic acid, thiamine, riboflavin

Intervention Type DRUG

Interventions

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Ursodeoxycholic acid, thiamine, riboflavin

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* CIS greater than or equal to 76, HADS less than or equal to 10
* ALT greater than upper limit of normal OR fatty liver on US

Exclusion Criteria

* Subjects who have diseases that can cause fatigue
* Subjects who are taking medication that can cause fatigue
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Daewoong Pharmaceutical Co. LTD.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Ilsan Paik Hospital

Ilsan, Kyung-gi-do, South Korea

Site Status

Countries

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South Korea

References

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Oh B, Choi WS, Park SB, Cho B, Yang YJ, Lee ES, Lee JH. Efficacy and safety of ursodeoxycholic acid composite on fatigued patients with elevated liver function and/or fatty liver: a multi-centre, randomised, double-blinded, placebo-controlled trial. Int J Clin Pract. 2016 Apr;70(4):302-11. doi: 10.1111/ijcp.12790. Epub 2016 Mar 20.

Reference Type DERIVED
PMID: 26997458 (View on PubMed)

Other Identifiers

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DW_UDCA003

Identifier Type: -

Identifier Source: org_study_id

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