NAVIGATE: Clinical Evaluation of superDimension™ Navigation System for Electromagnetic Navigation Bronchoscopy™

NCT ID: NCT02410837

Last Updated: 2021-05-10

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1388 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-04-16

Study Completion Date

2019-11-01

Brief Summary

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The purpose of this study is to evaluate outcomes following electromagnetic navigation bronchoscopy™ (ENB™) procedures using the superDimension™ navigation system.

Detailed Description

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This clinical trial information was submitted voluntarily under the applicable law and, therefore, certain submission deadlines may not apply. (That is, clinical trial information for this applicable clinical trial was submitted under section 402(j)(4)(A) of the Public Health Service Act and 42 CFR 11.60 and is not subject to the deadlines established by sections 402(j)(2) and (3) of the Public Health Service Act or 42 CFR 11.24 and 11.44.)

Conditions

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Lung Lesion(s) Requiring Evaluation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Electromagnetic Navigation Bronchoscopy

Intervention Type PROCEDURE

Other Intervention Names

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ENB superDimension

Eligibility Criteria

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Inclusion Criteria

* Subject presents with lung lesion(s) requiring evaluation
* Subject is willing and able to provide informed consent to participate in the study
* Subject is candidate for elective ENB™ procedure
* Subject is over the age of 18

Exclusion Criteria

* The subject is unable or unwilling to comply with study follow-up schedule
* The subject has participated in an investigational drug or device research study within 30 days of enrollment that would interfere with this study
* Female subjects who are pregnant or nursing as determined by standard site practices
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medtronic - MITG

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sandeep Khandhar, MD

Role: PRINCIPAL_INVESTIGATOR

Inova Fairfax Hospital

Erik Folch, MD

Role: PRINCIPAL_INVESTIGATOR

Massachusetts General Hospital

Locations

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University of Alabama at Birmingham

Birmingham, Alabama, United States

Site Status

Pulmonary Associates of Mobile, P.C.

Mobile, Alabama, United States

Site Status

Palo Alto Medical Foundation

Mountain View, California, United States

Site Status

Pulmonary and Sleep of Tampa Bay

Brandon, Florida, United States

Site Status

Ocala Lung and Critical Care

Ocala, Florida, United States

Site Status

Cancer Treatment Centers of America

Newnan, Georgia, United States

Site Status

The University of Chicago

Chicago, Illinois, United States

Site Status

Pulmonary and Critical Care Associates of Baltimore

Baltimore, Maryland, United States

Site Status

University of Michigan Health Systems

Ann Arbor, Michigan, United States

Site Status

Virtua Medical Group, PA

Marlton, New Jersey, United States

Site Status

University of Rochester

Rochester, New York, United States

Site Status

Carolina's Healthcare System

Charlotte, North Carolina, United States

Site Status

Duke University

Durham, North Carolina, United States

Site Status

East Carolina University

Greenville, North Carolina, United States

Site Status

Pinehurst Medical Center

Pinehurst, North Carolina, United States

Site Status

University of Cincinnati Physicians Company LLC

Cincinnati, Ohio, United States

Site Status

University Hospitals of Case Medical Center

Cleveland, Ohio, United States

Site Status

Cleveland Clinic

Cleveland, Ohio, United States

Site Status

Penn Highlands Healthcare

DuBois, Pennsylvania, United States

Site Status

UPMC - Shadyside Medical Center

Pittsburgh, Pennsylvania, United States

Site Status

Pulmonary Medicine Center of Chattanooga - Memorial Health

Chattanooga, Tennessee, United States

Site Status

Blount Memorial Hospital

Maryville, Tennessee, United States

Site Status

Vanderbilt University

Nashville, Tennessee, United States

Site Status

Seton Medical Center Austin

Austin, Texas, United States

Site Status

East Texas Medical Center

Tyler, Texas, United States

Site Status

Providence Health Center

Waco, Texas, United States

Site Status

Inova Fairfax Hospital

Falls Church, Virginia, United States

Site Status

Charleston Area Medical Center

Charleston, West Virginia, United States

Site Status

Gundersen Lutheran Medical Foundation, Inc

La Crosse, Wisconsin, United States

Site Status

AKH Linz

Linz, , Austria

Site Status

Salzburger Landesklinik (SALK)

Salzburg, , Austria

Site Status

Rigshospitalet - Copenhagen

Copenhagen, , Denmark

Site Status

University Hospitals of Saint Etienne France

Saint-Etienne, , France

Site Status

Azienda Ospedaliero Universitaria Careggi

Florence, , Italy

Site Status

IRCCS Azienda Ospedaliera Universitaria San Martino - IST

Genova, , Italy

Site Status

Hospital Fundacion Jimenez Diaz

Madrid, , Spain

Site Status

St. Bartholomew's Hospital

London, , United Kingdom

Site Status

Countries

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United States Austria Denmark France Italy Spain United Kingdom

References

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Bowling MR, Folch EE, Khandhar SJ, Kazakov J, Krimsky WS, LeMense GP, Linden PA, Murillo BA, Nead MA, Pritchett MA, Teba CV, Towe CW, Williams T, Anciano CJ. Fiducial marker placement with electromagnetic navigation bronchoscopy: a subgroup analysis of the prospective, multicenter NAVIGATE study. Ther Adv Respir Dis. 2019 Jan-Dec;13:1753466619841234. doi: 10.1177/1753466619841234.

Reference Type DERIVED
PMID: 30958102 (View on PubMed)

Khandhar SJ, Bowling MR, Flandes J, Gildea TR, Hood KL, Krimsky WS, Minnich DJ, Murgu SD, Pritchett M, Toloza EM, Wahidi MM, Wolvers JJ, Folch EE; NAVIGATE Study Investigators. Electromagnetic navigation bronchoscopy to access lung lesions in 1,000 subjects: first results of the prospective, multicenter NAVIGATE study. BMC Pulm Med. 2017 Apr 11;17(1):59. doi: 10.1186/s12890-017-0403-9.

Reference Type DERIVED
PMID: 28399830 (View on PubMed)

Folch EE, Bowling MR, Gildea TR, Hood KL, Murgu SD, Toloza EM, Wahidi MM, Williams T, Khandhar SJ. Design of a prospective, multicenter, global, cohort study of electromagnetic navigation bronchoscopy. BMC Pulm Med. 2016 Apr 26;16(1):60. doi: 10.1186/s12890-016-0228-y.

Reference Type DERIVED
PMID: 27113209 (View on PubMed)

Provided Documents

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Document Type: Study Protocol, Statistical Analysis Plan, and Informed Consent Form

View Document

Other Identifiers

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COVENBP0475

Identifier Type: -

Identifier Source: org_study_id

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