Early Markers of Radiation-Induced Cardiac Injury in Hodgkin Lymphoma Treated With Radiation Therapy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

5 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-04-30

Study Completion Date

2021-04-14

Brief Summary

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The purpose of this study is to evaluate if radiation and chemotherapy treatment cause cardiac abnormalities among survivors of Hodgkin's lymphoma.

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Detailed Description

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Conditions

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Hodgkin's Lymphoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Survivors of Hodgkin's lymphoma

Cardiac Magnetic Resonance Imaging and Echocardiogram

Cardiac Magnetic Resonance Imaging

Intervention Type PROCEDURE

A cardiac MRI will be performed.

Echocardiogram

Intervention Type PROCEDURE

An echocardiogram will be performed for the following information: M-mode, two-dimensional, Doppler blood flow measurements, and longitudinal strain and strain rate imaging

Interventions

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Cardiac Magnetic Resonance Imaging

A cardiac MRI will be performed.

Intervention Type PROCEDURE

Echocardiogram

An echocardiogram will be performed for the following information: M-mode, two-dimensional, Doppler blood flow measurements, and longitudinal strain and strain rate imaging

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Completed radiation and chemotherapy treatment for Hodgkin lymphoma involving the mediastinum.
* Patient must be ≥ 18 years at time of consent.

Exclusion Criteria

* Pregnant women at time of Cardiac MRI
* Contraindications to Cardiac MRI (contrast allergy, metal implants, medical devices)
* Glomerular filtration rate (GFR) \< 30, unless approved by Radiologist (UF Health Jacksonville Radiology Policy: Administration of Gadolinium-Based Contrast Agents).

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No