Trial Outcomes & Findings for A Trial to Evaluate Negative Pressure Incision Management System for Groin Wounds in Vascular Surgery Patients (NCT NCT02399111)

NCT ID: NCT02399111

Last Updated: 2016-11-21

Results Overview

This study was terminated prior to gathering of data.

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

9 participants

Primary outcome timeframe

30 days

Results posted on

2016-11-21

Participant Flow

Participant milestones

Participant milestones
Measure
Not Obese:BMI<30; Standard Care
Not obese: BMI\< 30; Standard Wound Care
Obese:BMI≥30; Standard Care
Obese: BMI ≥30; Standard Wound Care
Not Obese:BMI<30; Wound Vac
Using Prevena Incision Management System Prevena Incision Management System: The PIMS unit is a single patient use, battery-powered, disposable unit that delivers continuous negative 125 mmHg pressure to the closed surgical incision for a 7-day therapy period. It is an easy to use device that also provides audible and visual alerts for low battery, maximum canister volume, and leak conditions. Additional alerts include system error and device life-cycle expiration (8 days). It is contained in a water-resistant housing, which allows the Subject to lightly shower with the device. Wound fluids are contained within the 45 mL canister. For the purposes of this clinical investigation, canisters can be replaced as often as is needed. A carrying case is also provided with the therapy unit, to allow for patient mobility during the therapy period.
Obese:BMI≥30; Wound Vac
Using Prevena Incision Management System Prevena Incision Management System: The PIMS unit is a single patient use, battery-powered, disposable unit that delivers continuous negative 125 mmHg pressure to the closed surgical incision for a 7-day therapy period. It is an easy to use device that also provides audible and visual alerts for low battery, maximum canister volume, and leak conditions. Additional alerts include system error and device life-cycle expiration (8 days). It is contained in a water-resistant housing, which allows the Subject to lightly shower with the device. Wound fluids are contained within the 45 mL canister. For the purposes of this clinical investigation, canisters can be replaced as often as is needed. A carrying case is also provided with the therapy unit, to allow for patient mobility during the therapy period.
Overall Study
STARTED
4
1
4
0
Overall Study
COMPLETED
4
1
4
0
Overall Study
NOT COMPLETED
0
0
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

A Trial to Evaluate Negative Pressure Incision Management System for Groin Wounds in Vascular Surgery Patients

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Not Obese:BMI<30; Standard Care
n=4 Participants
Not obese:BMI\<30;Standard Wound Care
Obese:BMI≥30; Standard Care
n=1 Participants
Obese:BMI≥30;Standard Wound Care
Not Obese:BMI<30; Wound Vac
n=4 Participants
Using Prevena Incision Management System Prevena Incision Management System: The PIMS unit is a single patient use, battery-powered, disposable unit that delivers continuous negative 125 mmHg pressure to the closed surgical incision for a 7-day therapy period. It is an easy to use device that also provides audible and visual alerts for low battery, maximum canister volume, and leak conditions. Additional alerts include system error and device life-cycle expiration (8 days). It is contained in a water-resistant housing, which allows the Subject to lightly shower with the device. Wound fluids are contained within the 45 mL canister. For the purposes of this clinical investigation, canisters can be replaced as often as is needed. A carrying case is also provided with the therapy unit, to allow for patient mobility during the therapy period.
Obese:BMI≥30; Wound Vac
Using Prevena Incision Management System Prevena Incision Management System: The PIMS unit is a single patient use, battery-powered, disposable unit that delivers continuous negative 125 mmHg pressure to the closed surgical incision for a 7-day therapy period. It is an easy to use device that also provides audible and visual alerts for low battery, maximum canister volume, and leak conditions. Additional alerts include system error and device life-cycle expiration (8 days). It is contained in a water-resistant housing, which allows the Subject to lightly shower with the device. Wound fluids are contained within the 45 mL canister. For the purposes of this clinical investigation, canisters can be replaced as often as is needed. A carrying case is also provided with the therapy unit, to allow for patient mobility during the therapy period.
Total
n=9 Participants
Total of all reporting groups
Age, Categorical
Between 18 and 65 years
4 Participants
n=5 Participants
1 Participants
n=7 Participants
4 Participants
n=5 Participants
0 Participants
n=4 Participants
9 Participants
n=21 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
0 Participants
n=4 Participants
0 Participants
n=21 Participants
Gender
Female
2 Participants
n=5 Participants
1 Participants
n=7 Participants
0 Participants
n=5 Participants
0 Participants
n=4 Participants
3 Participants
n=21 Participants
Gender
Male
2 Participants
n=5 Participants
0 Participants
n=7 Participants
4 Participants
n=5 Participants
0 Participants
n=4 Participants
6 Participants
n=21 Participants
Age, Categorical
<=18 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
0 Participants
n=4 Participants
0 Participants
n=21 Participants

PRIMARY outcome

Timeframe: 30 days

This study was terminated prior to gathering of data.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 30 days

This study was terminated prior to collection of data.

Outcome measures

Outcome data not reported

Adverse Events

Not Obese:BMI<30; Standard Care

Serious events: 0 serious events
Other events: 1 other events
Deaths: 0 deaths

Obese:BMI≥30; Standard Care

Serious events: 0 serious events
Other events: 1 other events
Deaths: 0 deaths

Not Obese:BMI<30; Wound Vac

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Obese:BMI≥30; Wound Vac

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
Not Obese:BMI<30; Standard Care
n=4 participants at risk
Not obese:BMI\<30;Standard Wound Care
Obese:BMI≥30; Standard Care
n=1 participants at risk
Obese:BMI≥30;Standard Wound Care
Not Obese:BMI<30; Wound Vac
n=4 participants at risk
Using Prevena Incision Management System Prevena Incision Management System: The PIMS unit is a single patient use, battery-powered, disposable unit that delivers continuous negative 125 mmHg pressure to the closed surgical incision for a 7-day therapy period. It is an easy to use device that also provides audible and visual alerts for low battery, maximum canister volume, and leak conditions. Additional alerts include system error and device life-cycle expiration (8 days). It is contained in a water-resistant housing, which allows the Subject to lightly shower with the device. Wound fluids are contained within the 45 mL canister. For the purposes of this clinical investigation, canisters can be replaced as often as is needed. A carrying case is also provided with the therapy unit, to allow for patient mobility during the therapy period.
Obese:BMI≥30; Wound Vac
Using Prevena Incision Management System Prevena Incision Management System: The PIMS unit is a single patient use, battery-powered, disposable unit that delivers continuous negative 125 mmHg pressure to the closed surgical incision for a 7-day therapy period. It is an easy to use device that also provides audible and visual alerts for low battery, maximum canister volume, and leak conditions. Additional alerts include system error and device life-cycle expiration (8 days). It is contained in a water-resistant housing, which allows the Subject to lightly shower with the device. Wound fluids are contained within the 45 mL canister. For the purposes of this clinical investigation, canisters can be replaced as often as is needed. A carrying case is also provided with the therapy unit, to allow for patient mobility during the therapy period.
Infections and infestations
Infection
25.0%
1/4 • Number of events 1
100.0%
1/1 • Number of events 1
0.00%
0/4
0/0

Additional Information

Dr. Kambhampaty Krishnasastry

Northwell Health System

Phone: 516-233-3643

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place