Evaluation of the Diagnostic Value of PET (18F-FDG) in Chronic Graft Versus Host Disease (cGVH)
NCT ID: NCT02352064
Last Updated: 2017-02-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
26 participants
INTERVENTIONAL
2015-01-31
2018-01-31
Brief Summary
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PET-CT with 18F-FDG has already been evaluated in chronic inflammatory diseases such as Crohns disease with good sensitivity and specificity. It interest in the graft against the host was studied in acute forms of digestive and allows lesion mapping and monitoring the effectiveness of treatment.
Among patients with chronic GVHD scleroderma form, PET with 18F-FDG enabled to view musculoskeletal uptakes localized to the affected areas identified with MRI.
The investigators propose a study evaluating the sensitivity and specificity of the examination by PET-CT with 18F-FDG in the diagnosis of chronic GVHD compared to conventional diagnostic tools.
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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PET-CT at day 150+/-15 days
Patient will have PET (18-FDG) following allogeneic stem cell transplantation
PET (18-FDG)
Every patient will have a PET
Interventions
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PET (18-FDG)
Every patient will have a PET
Eligibility Criteria
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Inclusion Criteria
* Signed informed consent
* subject covered by a social security system
* Absence of contraindication to PET (18F-FDG)
* Allogeneic stem cell transplantation
Exclusion Criteria
* Pregnant or lactating women or women of childbearing potential not currently practicing an adequate method of contraception
* Age\<18 years
* Evolutive infectious disease
* glycemia \>10mmol/L
18 Years
ALL
No
Sponsors
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University Hospital, Caen
OTHER
Responsible Party
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Locations
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University Hospital
Caen, , France
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2014-A00724-43
Identifier Type: -
Identifier Source: org_study_id
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