Quality of Life of Stable Stroke Survivors in Pakistan

NCT ID: NCT02351778

Last Updated: 2015-01-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

350 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Study Completion Date

2014-06-30

Brief Summary

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In study the investigators sought to

1. Assess the quality of life experience in stable post stroke survivors in Pakistan and detail important factors influencing quality of life.
2. Explore the association between primary care giver's quality of life and stroke survivor's quality of life.
3. To validate the quality of life tools and experience via in depth interviews and focus group discussion with the primary care giver of stroke patients to report the quality of life of the primary care giver.

Detailed Description

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Disability caused by stroke has a detrimental impact on patients with social and physical consequences of stroke being equally devastating. Yet there are only few studies done in South Asia that explore holistically the cumulative impact of disability and quality of life on stroke survivors.

In Pakistan majority of stroke patients are cared by close family members and no inpatient rehabilitation services are available in Pakistan for stroke survivors. The amount of support from government is scarce and private systems are largely unregulated therefore the psychosocial problems in Pakistani stroke survivors are different from those experienced by stroke survivors in developed countries. It is proposed that the quality of life of stroke survivors in Pakistan will be worse as compared to stroke survivors in developed countries. However, due to existence of considerable family support even in absence of good government and environmental support systems we cannot be certain about this assumption. Since care givers provide all medical and social services to chronic stroke victims their quality of life and stress level also plays an important role in the care given to the stroke survivors.

We propose to conduct a cross-sectional study, in order to assess the quality of life in stroke survivors and its important predictors in Karachi. The domains which will be studied includes physical; in terms of severity of disability, which affects the person after stroke, social functioning; which includes the role of primary care giver and social support given to the stroke survivors, mental health; in which depression affects the life of stroke survivor badly after stroke.

Also to explore the perspective of the primary care giver for those important factors which affect the quality of life focus group discussions will be conducted in the study. This is a mixed methods observational analytical study.

Conditions

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Cerebrovascular Disease

Keywords

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Developing Countries Quality of Life Mixed Methods Validation Caregiver Burden

Study Design

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Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* All men and women of age greater than 18 years of age with medically confirmed diagnosis of stroke.
* Suffered stroke (3 months till 12 months), stable non fluctuating stroke which means no acute ongoing neurologic developments (Crescendo TIA, CEA planned, intervention needed, progressing stroke, fluctuating unexplained neurologic symptoms).
* With an identified primary care giver (This is a person who lives with the stroke patient, is familiar with the medical history and provides direct care e.g. feeding support, medication reminders, rehab. This person may be different from the legal surrogate e.g., son vs. daughter in law )

Exclusion Criteria

* Post procedure stroke like CABG, angiography, post-operative.
* Global aphasia with failure to communicate (NIHSS greater than 23).
* Dementia with failure to communicate (Minimental state of 22)
* With history of psychoactive substance abuse.
* Psychiatric morbidity like schizophrenia and other manic disorders.
* Suffering from chronic disease like terminal stage cancer and end stage renal disease.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Aga Khan University

OTHER

Sponsor Role lead

Responsible Party

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Dr. Ayeesha Kamran Kamal

Associate Professor Neurology,Director Stroke Fellowship Program

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Khalid W, Rozi S, Ali TS, Azam I, Mullen MT, Illyas S, Un-Nisa Q, Soomro N, Kamal AK. Quality of life after stroke in Pakistan. BMC Neurol. 2016 Dec 3;16(1):250. doi: 10.1186/s12883-016-0774-1.

Reference Type DERIVED
PMID: 27912744 (View on PubMed)

Other Identifiers

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5D43TW008660-04

Identifier Type: NIH

Identifier Source: org_study_id

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