Evaluate Effects of Personalized Patient Counselling for Enbrel® Therapy in Adults With Rheumatoid Arthritis

NCT ID: NCT02346877

Last Updated: 2017-03-27

Study Results

Results available

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE4

Total Enrollment

19 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-04-30

Study Completion Date

2015-10-31

Brief Summary

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This study will evaluate whether the effect of personalized patient counselling tool, Information-Motivation-Strategy (IMS) based on the results of the Beliefs about Medicines Questionnaire (BMQ) will improve persistence of Enbrel (etanercept) therapy at week 52 in subjects with rheumatoid arthritis over the historical control as estimated by the standard of care.

Detailed Description

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Conditions

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Persistence to Enbrel

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Standard of Care Cohort

The first 100 participants will be enrolled in the standard of care (control) cohort. These participants will receive treatment with Enbrel® (etanercept) in routine clinical practice and will complete a 52 week study period as per the investigator's standard of care.

Group Type NO_INTERVENTION

No interventions assigned to this group

Personalized Patient Counselling Cohort

Initiation of the personalized patient counselling cohort will begin after 75% of participants in the control cohort have been analyzed and shown not to have high persistence. Participants will receive Enbrel® (etanercept) therapy in routine clinical practice and personalized patient counselling based on the Information-Motivation-Strategy (IMS) model based on Beliefs about Medicines Questionnaire (BMQ) baseline results through a patient assistance program for patients on Enbrel (etanercept) therapy.

Group Type OTHER

Personalized Patient Counselling

Intervention Type BEHAVIORAL

In the interventional cohort participants enrolled on the study will receive personalized patient counselling using the IMS-model based on the baseline BMQ results through a patient assistance program for patients on Enbrel (Etanercept) therapy.

Interventions

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Personalized Patient Counselling

In the interventional cohort participants enrolled on the study will receive personalized patient counselling using the IMS-model based on the baseline BMQ results through a patient assistance program for patients on Enbrel (Etanercept) therapy.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Subject has provided informed consent prior to any study specific procedures
* diagnosed with rheumatoid arthritis and eligible for treatment with Enbrel® (etanercept)
* Subject has been prescribed and has access to commercial Enbrel® (etanercept) (50mg once weekly) according to the subject's health insurance
* Completion of all required safety assessments before starting treatment with Enbrel® (etanercept)

Exclusion Criteria

* previously received treatment with a biologic disease modifying antirheumatic drug (DMARD) and/or Tofacitinib.
* Malignancy (except nonmelanoma skin cancers, cervical or breast ductal carcinoma in situ) within the last 5 years
* refusal to consent to enroll in the Enliven program
* Currently receiving treatment in another investigational device or drug study, or less than 30 days since ending treatment on another investigational device or drug study(s)
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Amgen

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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MD

Role: STUDY_DIRECTOR

Amgen

Locations

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Research Site

Winnipeg, Manitoba, Canada

Site Status

Research Site

Fredericton, New Brunswick, Canada

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Research Site

Quispamsis, New Brunswick, Canada

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Research Site

St. John's, Newfoundland and Labrador, Canada

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Research Site

Hamilton, Ontario, Canada

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Research Site

Kingston, Ontario, Canada

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Research Site

Mississauga, Ontario, Canada

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Research Site

Ottawa, Ontario, Canada

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Research Site

Peterborough, Ontario, Canada

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Research Site

Montreal, Quebec, Canada

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Montreal, Quebec, Canada

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Québec, Quebec, Canada

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Research Site

Rimouski, Quebec, Canada

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Research Site

Sherbrooke, Quebec, Canada

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Research Site

Trois-Rivières, Quebec, Canada

Site Status

Countries

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Canada

Related Links

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http://www.amgentrials.com

AmgenTrials clinical trials website

Other Identifiers

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20130340

Identifier Type: -

Identifier Source: org_study_id

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