A Hemodynamic Comparison of Stationary and Portable Pneumatic Compression Devices

NCT ID: NCT02345642

Last Updated: 2017-10-16

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-02-28

Study Completion Date

2016-01-31

Brief Summary

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We are comparing two pneumatic compression devices, VenaFlow (stationary) and MCS (portable) in both the supine an standing position. We will start supine and will take 3 baseline measurements of venous velocity and then apply a device and take 3 measurements of the increase in peak venous velocity. We will repeat this with the second device. We will then have the subject stand and repeat the above with each device. We will randomize the order of the devices in the supine and standing position. This study will involve 10 healthy subjects of various ages and 10 total hip replacements (THR) patients.

Detailed Description

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Conditions

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Total Hip Arthroplasty

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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10 Healthy Patients without THA

The 10 test subjects of this study arm will be healthy volunteers of various ages that are willing to have the efficacy of pneumatic compression tested on them.

Group Type ACTIVE_COMPARATOR

ActiveCare+SFT Supine

Intervention Type DEVICE

VenaFlow Elite Supine

Intervention Type DEVICE

ActiveCare+SFT Standing

Intervention Type DEVICE

VenaFlow Elite Standing

Intervention Type DEVICE

10 Patients with THA on Post-Op Day 2

The 10 test subjects of this study arm will be primary THR patients of Dr. Westrich that have undergone uncomplicated THR surgery in which they are allowed to be full weight bearing by or before post-op day 2.

Group Type EXPERIMENTAL

ActiveCare+SFT Supine

Intervention Type DEVICE

VenaFlow Elite Supine

Intervention Type DEVICE

ActiveCare+SFT Standing

Intervention Type DEVICE

VenaFlow Elite Standing

Intervention Type DEVICE

Interventions

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ActiveCare+SFT Supine

Intervention Type DEVICE

VenaFlow Elite Supine

Intervention Type DEVICE

ActiveCare+SFT Standing

Intervention Type DEVICE

VenaFlow Elite Standing

Intervention Type DEVICE

Other Intervention Names

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Portable Pneumatic Compression Device Supine Stationary Pneumatic Compression Device Supine Portable Pneumatic Compression Device Standing Stationary Pneumatic Compression Device Standing

Eligibility Criteria

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Inclusion Criteria

Phase one: 10 healthy test subjects will be included of various ages. They will have each pneumatic compression device applied in the supine and then standing positions.

Phase two: 10 patients following THR on postoperative day #2 will be included. These patients will agree to participate in the study and have to be able to stand for approximately 10 minutes.

Exclusion Criteria

* Patients with lymphedema
* Patients with peripheral vascular disease (chronic venous insufficiency)
* Patients who do not wish to participate
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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DJO Incorporated

INDUSTRY

Sponsor Role collaborator

Hospital for Special Surgery, New York

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Lucian Warth, MD

Role: STUDY_DIRECTOR

Hospital for Special Surgery, New York

Locations

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Hospital for Special Surgery

New York, New York, United States

Site Status

Countries

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United States

References

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Westrich GH, Specht LM, Sharrock NE, Windsor RE, Sculco TP, Haas SB, Trombley JF, Peterson M. Venous haemodynamics after total knee arthroplasty: evaluation of active dorsal to plantar flexion and several mechanical compression devices. J Bone Joint Surg Br. 1998 Nov;80(6):1057-66. doi: 10.1302/0301-620x.80b6.8627.

Reference Type BACKGROUND
PMID: 9853503 (View on PubMed)

Westrich GH, Specht LM, Sharrock NE, Sculco TP, Salvati EA, Pellicci PM, Trombley JF, Peterson M. Pneumatic compression hemodynamics in total hip arthroplasty. Clin Orthop Relat Res. 2000 Mar;(372):180-91. doi: 10.1097/00003086-200003000-00020.

Reference Type BACKGROUND
PMID: 10738427 (View on PubMed)

Johanson NA, Lachiewicz PF, Lieberman JR, Lotke PA, Parvizi J, Pellegrini V, Stringer TA, Tornetta P 3rd, Haralson RH 3rd, Watters WC 3rd. Prevention of symptomatic pulmonary embolism in patients undergoing total hip or knee arthroplasty. J Am Acad Orthop Surg. 2009 Mar;17(3):183-96. doi: 10.5435/00124635-200903000-00007.

Reference Type BACKGROUND
PMID: 19264711 (View on PubMed)

Pitto RP, Hamer H, Heiss-Dunlop W, Kuehle J. Mechanical prophylaxis of deep-vein thrombosis after total hip replacement a randomised clinical trial. J Bone Joint Surg Br. 2004 Jul;86(5):639-42. doi: 10.1302/0301-620x.86b5.14763.

Reference Type BACKGROUND
PMID: 15274256 (View on PubMed)

Ben-Galim P, Steinberg EL, Rosenblatt Y, Parnes N, Menahem A, Arbel R. A miniature and mobile intermittent pneumatic compression device for the prevention of deep-vein thrombosis after joint replacement. Acta Orthop Scand. 2004 Oct;75(5):584-7. doi: 10.1080/00016470410001466.

Reference Type BACKGROUND
PMID: 15513491 (View on PubMed)

Froimson MI, Murray TG, Fazekas AF. Venous thromboembolic disease reduction with a portable pneumatic compression device. J Arthroplasty. 2009 Feb;24(2):310-6. doi: 10.1016/j.arth.2007.10.030. Epub 2008 Apr 8.

Reference Type BACKGROUND
PMID: 18534456 (View on PubMed)

Murakami M, McDill TL, Cindrick-Pounds L, Loran DB, Woodside KJ, Mileski WJ, Hunter GC, Killewich LA. Deep venous thrombosis prophylaxis in trauma: improved compliance with a novel miniaturized pneumatic compression device. J Vasc Surg. 2003 Nov;38(5):923-7. doi: 10.1016/s0741-5214(03)00792-4.

Reference Type BACKGROUND
PMID: 14603195 (View on PubMed)

Colwell CW Jr, Spiro TE, Trowbridge AA, Morris BA, Kwaan HC, Blaha JD, Comerota AJ, Skoutakis VA. Use of enoxaparin, a low-molecular-weight heparin, and unfractionated heparin for the prevention of deep venous thrombosis after elective hip replacement. A clinical trial comparing efficacy and safety. Enoxaparin Clinical Trial Group. J Bone Joint Surg Am. 1994 Jan;76(1):3-14. doi: 10.2106/00004623-199401000-00002.

Reference Type BACKGROUND
PMID: 8288662 (View on PubMed)

Geerts WH, Bergqvist D, Pineo GF, Heit JA, Samama CM, Lassen MR, Colwell CW. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008 Jun;133(6 Suppl):381S-453S. doi: 10.1378/chest.08-0656.

Reference Type BACKGROUND
PMID: 18574271 (View on PubMed)

Silbersack Y, Taute BM, Hein W, Podhaisky H. Prevention of deep-vein thrombosis after total hip and knee replacement. Low-molecular-weight heparin in combination with intermittent pneumatic compression. J Bone Joint Surg Br. 2004 Aug;86(6):809-12. doi: 10.1302/0301-620x.86b6.13958.

Reference Type BACKGROUND
PMID: 15330019 (View on PubMed)

Edwards JZ, Pulido PA, Ezzet KA, Copp SN, Walker RH, Colwell CW Jr. Portable compression device and low-molecular-weight heparin compared with low-molecular-weight heparin for thromboprophylaxis after total joint arthroplasty. J Arthroplasty. 2008 Dec;23(8):1122-7. doi: 10.1016/j.arth.2007.11.006. Epub 2008 Apr 2.

Reference Type BACKGROUND
PMID: 18534421 (View on PubMed)

Related Links

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http://www.djoglobal.com/products/venaflow/venaflow-elite-system

VenaFlow Elite Description on DJO Global's website

http://www.mcsmed.com/activecare_sft_2.html

ActiveCare+SVT Description on MCS's website

Other Identifiers

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14064

Identifier Type: -

Identifier Source: org_study_id