A Clinical Study of Subclinical Enthesitis and Synovitis in Patients With Vulgaris Psoriasis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-03-31

Study Completion Date

2016-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

A clinical study of subclinical enthesitis and synovitis in patients with vulgaris psoriasis

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Prospective Study of Classification and Activity Assessment of Psoriatic Arthritis Based on Power Doppler (PD) Ultrasonography (PDUS)

NCT06730334

Psoriatic Arthritis Secukinumab Ultrasonography

RECRUITING

Tumor Necrosis Factors (TNF)-α Blockade for Psoriatic Arthritis

NCT00432406

Psoriatic Arthritis

COMPLETED PHASE4

Ultrasound Enthesitis Response in Psoriatic Arthritis

NCT03955861

Psoriatic Arthritis Psoriasis Enthesitis

COMPLETED

Comparison of the Frequency of Subclinic Synovitis in the Distal Interphalangeal Joints of the Hand in Psoriasis Patients

NCT04750993

Psoriasis Synovitis

COMPLETED

Study Evaluating Workload, Clinical and Therapeutic Management of Psoriatic Arthritis

NCT00580632

Psoriatic Arthritis

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

A total of 100 patients with vulgaris psoriasis and 100 age-matched controls with other skin diseases, all without musculoskeletal diseases, will be recruited. They will undergo dermatological assessment and a blinded PDUS evaluation. Clinical assessment included demographics, severity of psoriasis, musculoskeletal clinical examination and sport activities. PDUS evaluation consisted of the detection of grey scale (GS) synovitis and synovial PD signal in joints of extremities, GS enthesopathy and entheseal PD signal in entheses of lower limbs.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Vulgaris Psoriasis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

case group

100 patients with vulgaris psoriasi without arthritis

PDUS examination

Intervention Type OTHER

control group

100 age-matched patients with other skin diseases without arthritis

PDUS examination

Intervention Type OTHER

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

PDUS examination

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* age≥18years
* patients with vulgaris psoriasis(dur
* patients with other skin diseases without musculoskeletal disorders
* no joint involvement and no clinical symptoms and signs of enthesitis and synovitis

Exclusion Criteria

* BMI≥24
* have history of gout or arthritis or peripheral neurological disease of lower extremity or trauma
* have received any systemic therapy(i.e.NSAIDs, corticosteroids, immunosuppressants, retinoids or biological agents) in 3 months
* pregnant or breast-feeding

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes