A Comparison of Supraglottic Airway Devices

NCT ID: NCT02339519

Last Updated: 2015-12-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-01-31

Study Completion Date

2015-06-30

Brief Summary

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This study aimed to compare the advantages and disadvantages of LMA Supreme, LMA Classic and LMA Fastrach regarding ease of insertion, repositioning, insertion time, effects on hemodynamic parameters, provision of adequate and safe airway, and oropharyngeal and systemic complications.

Detailed Description

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As a result of studies regarding the provision of an airway which is less invasive than intubation but safer than mask to maintain patency of airway after anesthesia induction in brief surgical interventions, supraglottic airway devices have been introduced into practice. They are inserted to glottic entry via the oral route and can be used in emergent conditions where tracheal intubation and mask anesthesia are challenging.

Classic LMA was first introduced by Archie Brain, MD in 1988, and consists of a mask with a surrounding inflatable bag compatible to the shape of the hypopharynx and a tube that has a 30° angle with a mask.

Fastrach LMA ( LMA Fastrach: LMA North America. Inc. San Diego. CA) was first introduced in 1997 and has similar features to the LMA Classic, but it is designed to provide upper airway during intubation via blind intubation or fiberoptic assistance. It has a rigid handle that allows one-handed insertion, removal or adjustment.

Supreme LMA, first introduced in April, 2007, is a novel, sterile, single use, new generation supraglottic airway device which provides more rapid and higher volume gas passage through airway and can be inserted in a rapid and safe manner because of the advanced cuff and airway tube. The integrated gastric canal facilitates gastric aspiration.

Supraglottic airway devices seem to have advantages over each other in different aspects due to their distinct features. In literature, there are studies comparing various LMA types for different features. However, to best of our knowledge, there is no study comparing these 3 types of LMA regarding these parameter. This is the main point of difference of our study.

Conditions

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Airway Management

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Investigators

Study Groups

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group LMA supreme

Patients who received Laryngeal Mask Airway; LMA supreme

Group Type ACTIVE_COMPARATOR

LMA SUPREME

Intervention Type DEVICE

Supreme LMA is a novel, sterile, single use, new generation supraglottic airway device which provides more rapid and higher volume gas passage through airway and can be inserted in a rapid and safe manner.

group LMA classic

Patients who received Laryngeal Mask Airway; LMA classic

Group Type ACTIVE_COMPARATOR

LMA CLASSIC

Intervention Type DEVICE

Classic LMA consists of a mask with a surrounding inflatable bag compatible to the shape of the hypopharynx and a tube that has a 30° angle with a mask.

group Fastrach

Patients who received Laryngeal Mask Airway; LMA fastrach

Group Type ACTIVE_COMPARATOR

LMA FASTRACH

Intervention Type DEVICE

Fastrach LMA has similar features to the LMA Classic, but it is designed to provide upper airway during intubation via blind intubation or fiberoptic assistance. It has a rigid handle that allows one-handed insertion, removal or adjustment.

Interventions

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LMA CLASSIC

Classic LMA consists of a mask with a surrounding inflatable bag compatible to the shape of the hypopharynx and a tube that has a 30° angle with a mask.

Intervention Type DEVICE

LMA FASTRACH

Fastrach LMA has similar features to the LMA Classic, but it is designed to provide upper airway during intubation via blind intubation or fiberoptic assistance. It has a rigid handle that allows one-handed insertion, removal or adjustment.

Intervention Type DEVICE

LMA SUPREME

Supreme LMA is a novel, sterile, single use, new generation supraglottic airway device which provides more rapid and higher volume gas passage through airway and can be inserted in a rapid and safe manner.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* normotensive patients with mouth aperture \> 3 cm,
* thyromental distance \> 6 cm,
* sternomental distance \> 12.5 cm,
* body mass index \< 35 kg m-2 were included in the study.

Exclusion Criteria

* patients with ASA III-IV,
* those with a history of gastroesophageal reflux,
* pregnancy,
* cardiovascular and central nerve system disease,
* those with difficulty in cooperation,
* those undergoing intracranial, intraabdominal and Ear-nose-throat surgeries were excluded from study.

None of the methods changed after commencement of the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Umraniye Education and Research Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Gulsah Karaoren

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Erdal Komur, MD

Role: PRINCIPAL_INVESTIGATOR

Istanbul Umraniye Education and Research Hospital

Locations

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Istanbul Umraniye Education and Research Hospital

Istanbul, Turkey, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Timmermann A, Cremer S, Heuer J, Braun U, Graf BM, Russo SG. [Laryngeal mask LMA Supreme. Application by medical personnel inexperienced in airway management]. Anaesthesist. 2008 Oct;57(10):970-5. doi: 10.1007/s00101-008-1425-8. German.

Reference Type BACKGROUND
PMID: 18712321 (View on PubMed)

Seet E, Rajeev S, Firoz T, Yousaf F, Wong J, Wong DT, Chung F. Safety and efficacy of laryngeal mask airway Supreme versus laryngeal mask airway ProSeal: a randomized controlled trial. Eur J Anaesthesiol. 2010 Jul;27(7):602-7. doi: 10.1097/eja.0b013e32833679e3.

Reference Type BACKGROUND
PMID: 20540172 (View on PubMed)

Other Identifiers

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GK4

Identifier Type: -

Identifier Source: org_study_id