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High Intensity Interval Training in Geriatrics

NCT ID: NCT02318459

Last Updated: 2016-11-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-05-31

Study Completion Date

2016-02-29

Brief Summary

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This is a pilot study for evaluating the feasibility of using High Intensity Interval Training in geriatric hospitalized patients compared to the standard current rehabilitation practice.

Detailed Description

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High Intensity Interval Training (HIIT) has shown a superior effectiveness and efficiency when compared to Moderate Intensity Continuous Training (MICT) in several types of patients and in healthy subjects. There are no data on HIIT in a general geriatric population. This study is a pilot study evaluating the feasibility of using HIIT in geriatric hospitalized patients compared to the standard current rehabilitation practice without HIIT. It is our desire to perform a larger randomized comparative trial between HIIT and MICT if the pilot study proves its feasibility.

Conditions

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Muscle Weakness Gait, Unsteady

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

NONE

Study Groups

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high intensity interval training-HIIT

HIIT 4 times a week, 30 minutes duration

Group Type EXPERIMENTAL

high intensity interval training-HIIT

Intervention Type OTHER

HIIT 4 times a week, 30 minutes duration

Traditionnal rehabilitation

Traditionnal group rehabilitation 3 times a week, 1 hour duration.

Group Type ACTIVE_COMPARATOR

Traditionnal group rehabilitation

Intervention Type OTHER

Traditionnal group rehabilitation, 3 times a week, 1 hour duration

Interventions

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high intensity interval training-HIIT

HIIT 4 times a week, 30 minutes duration

Intervention Type OTHER

Traditionnal group rehabilitation

Traditionnal group rehabilitation, 3 times a week, 1 hour duration

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients aged 65 years and older hospitalized for rehabilitation after an acute medical condition
* Expected duration of the rehabilitation ≥ 2 weeks
* Ability to follow instructions to perform a Timed up and Go Test
* Ability to perform exercises
* Willing to participate in 4 sessions of HIIT per week for 2 weeks

Exclusion Criteria

* Any acute condition with tachycardia, hypotension or fever.
* Abnormal cycle ergometer stress test with
* significant ECG modification
* decrease of more than 20 mmHg of the blood pressure with exercise
* angina
* ST depression at a workload \<6 METs
* Inability to reach an intensity of 15/20 in the Borg's scale of perceived exertion
* Any unresolved acute medical or surgical condition of the following kind:
* acute heart failure
* acute coronary syndrome \< 1 month
* strole \< 1 month
* active pericarditis / myocarditis / endocarditis
* thromboembolic disease with \< 2 weeks of anticoagulation
* acute infection requiring intravenous treatment
* ongoing intravenous perfusion
* surgery \< 2 months
* recent bone fracture
* Previous episode of primary cardiac arrest (ie, cardiac arrest that did not occur in the presence of an acute myocardial infarction or during a cardiac procedure).
* Severe heart failure (NYHA III and IV)
* Severe stenotic or regurgitant valvular disease
* Uncontrolled hypertension at rest (SBP≥160mmHg, DBP≥100mmHg)
* Uncontrolled dysrhythmia
* Non-sustained ventricular tachycardia with exercise
* Implanted defibrillator
* Obstructive cardiomyopathy
* Resting HR \> 100/min
* Severe peripheral artery disease
* Severe COPD (VEMS \< 50%)
* Exercise-induced asthma
* Oxygen dependency
* Muscular-skeletal anomaly that may limit exercise participation
* Delirium
* Inability to follow instructions
* Inability to consent
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Geneva

OTHER

Sponsor Role lead

Responsible Party

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Jean-Luc Reny

Head of division, Internal medicine and rehabilitation Trois-Chêne

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jean-Luc Reny, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Geneva

Locations

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Hôpital des Trois-Chêne (HUG)

Geneva, Thônex, Switzerland

Site Status

Countries

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Switzerland

References

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Pires Peixoto R, Trombert V, Poncet A, Kizlik J, Gold G, Ehret G, Trombetti A, Reny JL. Feasibility and safety of high-intensity interval training for the rehabilitation of geriatric inpatients (HIITERGY) a pilot randomized study. BMC Geriatr. 2020 Jun 5;20(1):197. doi: 10.1186/s12877-020-01596-7.

Reference Type DERIVED
PMID: 32503465 (View on PubMed)

Other Identifiers

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13-257

Identifier Type: -

Identifier Source: org_study_id