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Ocular Surface Dry Eye Microbiome

NCT ID: NCT02306668

Last Updated: 2014-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-02-28

Study Completion Date

2016-12-31

Brief Summary

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The investigators seek to characterize the identity of all microorganisms residing on the eye's surface (conjunctiva) in healthy eyes and those with dry eye syndrome, using a combination of analyses. Dry eye disease is thought to have an inflammatory basis and in the vast majority of cases the cause of the chronic inflammatory condition is unknown.

Detailed Description

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Conditions

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Dry Eyes

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Ocular surface discomfort

There are no interventions with this observational study

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* dry eye syndrome with OSDI score greater than 60
* control group with OSDI score less than 30

Exclusion Criteria

* recent history of contact lens wear
* use of topical antibiotics or prescription eye medication in past 6 months
* penetrating ocular surgery in the last 12 months
* age less than 18 years
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Washington

OTHER

Sponsor Role lead

Responsible Party

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Russell Van Gelder

Professor and Chair, Department of Ophthalmology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Russell Van Gelder, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

UW Medicine Eye Institute

Locations

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UW Medicine Eye Institute

Seattle, Washington, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Sue Rath, COT

Role: CONTACT

[email protected]
206-897-4331

Facility Contacts

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Sue Rath

Role: primary

[email protected]

Other Identifiers

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46093-B

Identifier Type: -

Identifier Source: org_study_id