Study Results
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Basic Information
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COMPLETED
NA
31 participants
INTERVENTIONAL
2012-01-31
2012-12-31
Brief Summary
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Detailed Description
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Inclusion criteria were:
* Patients older than 18 years old having at least 4 teeth with cervical buccal lesions sensitive to tactile and thermal/evaporation stimuli. (moderate / severe pain by EVA)
* Teeth with surface loss on the buccal cervical area with indication of resin-composite-based restoration.
Exclusion criteria were:
* Systemic diseases related to chronic pain
* Pregnancy
* Recent periodontal surgery, orthodontic treatment or desensitizing treatment within the last 3 months.
* In treatment with NSAIDs
* Teeth with caries or restorations
* Incisor teeth (to avoid cross innervation).
At baseline, two calibrated examiners (kappa \>0,75) evaluated teeth sensitivity. Tactile stimulus consisted of probing the buccal cervical surface of the teeth with North-Carolina periodontal probe (Hu-Friedy). Evaporation stimulus consisted in direct air pressure application with three-in-one syringe for one second at 60 psi at room temperature, perpendicular to the tooth, 1 cm away from the surface, protecting the adjacent teeth with cotton rolls. Patients quantified their pain caused by both stimuli through VAS (Visual Analogue Scale).
Pocock method was used to allocate the groups, so they presented similar distribution according to VAS (visual analogue scale) results recorded at baseline.
The assigned groups were:
* Z250 (n=30) Treated with distilled water (placebo) and restored with a methacrylate resin-based-composite (Z250, 3M ESPE, shade: A3)
* P90 (n=30) Treated with distilled water (placebo) and restored with a silorane resin-based-composite.
* OA/Z250 (n=31) treated with 0.5% oxalic acid (Desenssiv, SSWhite) and restored with a methacrylate resin-based-composite (Z250, 3M ESPE, shade: A3)
* OA/P90 (n=31) treated with 0,5% oxalic acid (Desenssiv SSWhite) and restored with a silorane resin-based-composite (Filtek Silorane p90, £M ESPE, shade:) Blinding Oxalic acid and distilled water were applied with micro brush, brushing for 1 minute, and then rinsed with water. Restorations were made following manufacturer instructions. The adhesive system Single Bond 2 (3M ESPE) was used with resin-based-composite Z250 and its own adhesive system was used for Filtek Silorane P90. To ensure the double-blind aspect of the trial, bottles of oxalic acid and distilled water were covered so operator could not recognized them, and the same was done with both types of resin-based-composites. Patients were also not aware of which tooth corresponded with which treatment.
Clinical evaluations The same two clinical examiners, than at baseline, evaluated teeth sensitivity after 30, 60, 90, 180 and 360 days of placing the restorations. Response of pain scored with VAS was recorded after tactile and evaporation stimuli. This was performed in the same manner than at baseline, but the tactile stimulus was performed probing around the tooth/restoration margin with North-Caroline periodontal probe (Hu-Friedy).
Statistical analysis The sample size was calculated with a statistical power (0.95) considering the sensitivity by EVA as principal outcome, with a confidence level (95%) resulting in n=28 , considering the reported drop-out was added a 5%.
SPSS (SPSS, Chicago, IL, USA) was used for the statistical analyzes of this study. Differences between groups were analyzed with Wilcoxon and Mann-Whitney test. For the multiple comparisons between groups was used Friedman test. The significance level of this study was set at 0.05.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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z250 resin composite
(n=31) Treated with distilled water (placebo) and restored with a methacrylate resin-based-composite (Z250, 3M ESPE, shade: A3)
No interventions assigned to this group
z250 resin composite + oxalic acid
(n=31) treated with 0.5% oxalic acid (Desenssiv, SSWhite)(intervention)// and restored with a methacrylate resin-based-composite (Z250, 3M ESPE, shade: A3)
with 0,5% oxalic acid (Desenssiv SSWhite)
with 0,5% oxalic acid (Desenssiv SSWhite) , desensitizer for sensivity cervical lesions on tooth
p 90 resin composite
(n=31) Treated with distilled water (placebo) and restored with a silorane resin-based-composite.
No interventions assigned to this group
p 90 resin composite + oxalic acid
(n=31) treated with 0,5% oxalic acid (Desenssiv SSWhite)(Intervention)/ and restored with a silorane resin-based-composite (Filtek Silorane p90, £M ESPE, shade:)
with 0,5% oxalic acid (Desenssiv SSWhite)
with 0,5% oxalic acid (Desenssiv SSWhite) , desensitizer for sensivity cervical lesions on tooth
Interventions
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with 0,5% oxalic acid (Desenssiv SSWhite)
with 0,5% oxalic acid (Desenssiv SSWhite) , desensitizer for sensivity cervical lesions on tooth
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Teeth with surface loss on the buccal cervical area with indication of resin-composite-based restoration.
Exclusion Criteria
* Pregnancy
* Recent periodontal surgery, orthodontic treatment or desensitizing treatment within the last 3 months.
* In treatment with NSAIDs
* Teeth with caries or restorations
* Incisor teeth (to avoid cross innervation).
18 Years
ALL
Yes
Sponsors
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University of Chile
OTHER
Responsible Party
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Eduardo Fernandez
Prof.Eduardo Fernández G.
Principal Investigators
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Eduardo Fernandez, Prof.
Role: PRINCIPAL_INVESTIGATOR
University of Chile
References
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Barrientos C, Xaus G, Leighton C, Martin J, Gordan VV, Moncada G. Oxalic acid under adhesive restorations as a means to reduce dentin sensitivity: a four-month clinical trial. Oper Dent. 2011 Mar-Apr;36(2):126-32. doi: 10.2341/09-364-C.
Other Identifiers
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2012/03
Identifier Type: -
Identifier Source: org_study_id