Study of Tumor Metabolism by Isotopic Tagging in Patients With High-grade Glioma (CARBONOMIC)
NCT ID: NCT02305056
Last Updated: 2018-05-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
TERMINATED
PHASE1
6 participants
INTERVENTIONAL
2014-09-30
2018-01-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Dose Escalation Radiotherapy With Modulation of Intensity and Integrated Boost (SIB-IMRT) in the Treatment of Glioblastomas in Adults
NCT01043536
11C-methionine in Diagnostics and Management of Glioblastoma Multiforme Patients (GlioMET)
NCT05608395
Randomized Phase 2 With CpG-ODN in Malignant Glioblastoma
NCT00190424
Phase III Study Comparing 2 Brain Conformational Radiotherapy in Combination With Chemotherapy in the Treatment of Glioblastoma
NCT01507506
Hyperpolarized Carbon-13 (13C) Pyruvate Imaging in Patients With Glioblastoma
NCT04019002
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
C13 N15 Valine
Intervention C13 N15 Valine
C13 N15 Valine
C13 N15 Valine administration
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
C13 N15 Valine
C13 N15 Valine administration
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* patient affiliated to social security or similarly regime
* informed consent form signed
* High-grade Glioma tumor suspicion
* Resective surgery indication
* Hematological assessment :
* neutrophils \> 1500/mm3
* Platelet \> 150 000
* blood Creatinin normal
* alkaline Phosphatases and transaminases no more than two times normal
* Bilirubin \< 1.5 times normal
* Intratumoral hemorrhage MRI detected
* Treatment anticoagulant or antisludge treatments
* Active Infections and non controled or medical affection or psychiatric intercurrent non treated
* Evolutive cerebral oedema without corticoid response
* Non controled Epilepsy without antiepileptics response
* Karnofsky score \< 40%
* Weight \> 100 kg
* No possibility of resective surgery
Exclusion Criteria
* Ward of court or under guardianship
* Adult unable to express their consent
* Person deprived of freedom by judicial or administrative decision
* Person hospitalized without their consent
* Person under legal protection
* Precedent complete macroscopic tumor resective surgery
18 Years
90 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
National Cancer Institute, France
OTHER_GOV
University Hospital, Grenoble
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
François BERGER, Pr
Role: PRINCIPAL_INVESTIGATOR
University Grenoble Hospital
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
CLINATEC
Grenoble, , France
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
CARBONOMIC
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.