Model 20105 Lead Study

NCT ID: NCT02301429

Last Updated: 2016-10-26

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-11-30

Study Completion Date

2016-07-31

Brief Summary

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The purpose of this study is to evaluate the implant procedure and feasibility of a new lead developed to pace and sense the left chambers of the heart.

Detailed Description

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Conditions

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Sick Sinus Node Syndrome

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Model 20105

Receiving the model 20105 Lead

Group Type EXPERIMENTAL

Model 20105

Intervention Type DEVICE

implant and follow-up of study device

Interventions

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Model 20105

implant and follow-up of study device

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Subject has Cardiac pacing indication for sinus node dysfunction (dual chamber pacemaker)
* Subject has signed and dated the study-specific informed consent form
* Subject is 18 years of age or older
* Subject is willing, able and committed to participate in Baseline and Follow-up and study procedures for the full length of the study

Exclusion Criteria

* Subject is indicated for BiV pacemaker or ICD
* Subject is pacing dependent
* Subject has a previous Pacemaker System
* Subject has known coronary venous vasculature that is inadequate for lead placement
* Subject has unstable angina pectoris or has had an acute myocardial infarction (MI) within the last month
* Subject has had a coronary artery bypass graft (CABG) or percutaneous transluminal coronary angioplasty (PTCA) within the past three months
* Subject is not in sinus rhythm at implant
* Subject has had a heart transplant (patients waiting for heart transplants are allowed in the study)
* Subject has known renal insufficiency that would prevent them from receiving an occlusive venogram during the implant procedure
* Subject is contraindicated for \<1mg dexamethasone acetate
* Subject is enrolled in any concurrent drug and/or device study that may confound the results of this study
* Subject has a terminal illness and is not expected to survive more than 6 months
* Subject is a pregnant woman or woman of childbearing potential not on adequate birth control.
* Subject is employed by Medtronic or by the department of any of the investigators or is a close relative of any of the investigators.
* Legal incapacity or evidence that a subject cannot understand the purpose and risks of the study
* Subject is unable to tolerate an urgent thoracotomy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medtronic BRC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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London Teaching Hospital

London, , Canada

Site Status

Reinier de Graaf Hospital

Delft, , Netherlands

Site Status

NUHCS, National University Hospital

Singapore, , Singapore

Site Status

Milpark hospital

Johannesburg, , South Africa

Site Status

Countries

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Canada Netherlands Singapore South Africa

Other Identifiers

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LV DDD

Identifier Type: -

Identifier Source: org_study_id