Trial Outcomes & Findings for CeraVe Cream Compared to Desitin Paste for Treating Diaper Dermatitis in Infants (NCT NCT02299206)

NCT ID: NCT02299206

Last Updated: 2018-03-13

Results Overview

For each visit the study doctor will assess the diaper dermatitis severity with a Diaper Dermatitis Severity Score tool. In Addition, location of clinically apparent involved area will be shaded by hand onto diagram by the research personnel. Scores will be compared.

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

4 participants

Primary outcome timeframe

14 days

Results posted on

2018-03-13

Participant Flow

Arms are combined for overall number of participants. Due to the low number of subjects, data will not be analyzed and the arm assignment for the subjects was not determined.

Participant milestones

Participant milestones
Measure
CeraVe Baby Diaper Rash Cream/Desitin Maximum Strength Origina
Healthy 3-18 months old infants with mild to moderate diaper dermatitis. CeraVe Baby Diaper Rash Cream: Parents/caregivers of subjects will administer CeraVe Baby Diaper Rash Cream (ingredients: Zinc oxide 10mg in 1g (1%) and dimethicone 10mg in 1g) or Desitin Maximum Strength Original Paste (ingredients: Zinc Oxide 40%) with each diaper change throughout the course of the study period. The product can be applied liberally as needed. Diapers and skin cleansing interventions will stay constant throughout the treatment period.
Overall Study
STARTED
4
Overall Study
COMPLETED
2
Overall Study
NOT COMPLETED
2

Reasons for withdrawal

Reasons for withdrawal
Measure
CeraVe Baby Diaper Rash Cream/Desitin Maximum Strength Origina
Healthy 3-18 months old infants with mild to moderate diaper dermatitis. CeraVe Baby Diaper Rash Cream: Parents/caregivers of subjects will administer CeraVe Baby Diaper Rash Cream (ingredients: Zinc oxide 10mg in 1g (1%) and dimethicone 10mg in 1g) or Desitin Maximum Strength Original Paste (ingredients: Zinc Oxide 40%) with each diaper change throughout the course of the study period. The product can be applied liberally as needed. Diapers and skin cleansing interventions will stay constant throughout the treatment period.
Overall Study
Lost to Follow-up
1
Overall Study
Withdrawal by Subject
1

Baseline Characteristics

CeraVe Cream Compared to Desitin Paste for Treating Diaper Dermatitis in Infants

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
CeraVe Baby Diaper Rash Cream/Desitin Maximum Strength Origina
n=4 Participants
Healthy 3-18 months old infants with mild to moderate diaper dermatitis. CeraVe Baby Diaper Rash Cream: Parents/caregivers of subjects will administer CeraVe Baby Diaper Rash Cream (ingredients: Zinc oxide 10mg in 1g (1%) and dimethicone 10mg in 1g) or Desitin Maximum Strength Original Paste (ingredients: Zinc Oxide 40%) with each diaper change throughout the course of the study period. The product can be applied liberally as needed. Diapers and skin cleansing interventions will stay constant throughout the treatment period.
Age, Continuous
11.5 months
STANDARD_DEVIATION 1.73 • n=5 Participants
Sex: Female, Male
Female
3 Participants
n=5 Participants
Sex: Female, Male
Male
1 Participants
n=5 Participants

PRIMARY outcome

Timeframe: 14 days

Population: Study was terminated prior to analysis due to low enrollment.

For each visit the study doctor will assess the diaper dermatitis severity with a Diaper Dermatitis Severity Score tool. In Addition, location of clinically apparent involved area will be shaded by hand onto diagram by the research personnel. Scores will be compared.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 7 days

Population: Study was terminated prior to analysis due to low enrollment.

For each visit the study doctor will assess the diaper dermatitis severity with a Diaper Dermatitis Severity Score tool. In Addition, location of clinically apparent involved area will be shaded by hand onto diagram by the research personnel. Scores will be compared.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 14 days

Population: Study was terminated prior to analysis due to low enrollment.

Parent/caregivers will be asked to complete a daily diary that asks about changes in their baby's diaper dermatitis, a Visual Analogue Scale severity assessment of their baby's diaper dermatitis, and observations related to product use and the baby's comfort level

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 14 days

Population: Study was terminated prior to analysis due to low enrollment.

Parent/caregivers will be asked to complete a daily diary that asks about changes in their baby's diaper dermatitis, a VAS severity assessment of their baby's diaper dermatitis, and observations related to product use and the baby's comfort level

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 14 days

Population: Study was terminated prior to analysis due to low enrollment.

Parents/caregivers will be given a questionnaire rating the use of the study products.

Outcome measures

Outcome data not reported

Adverse Events

CeraVe Baby Diaper Rash Cream/Desitin Maximum Strength Origina

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dermatology CTU

Northwestern University

Phone: 312-503-5944

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place