Triple Combination Therapy of Choroidal Neovascularization in AMD, a Cost Effect and Efficient Therapeutic Treatment

NCT ID: NCT02287298

Last Updated: 2016-04-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-08-31

Study Completion Date

2015-12-31

Brief Summary

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We propose to undertake a retrospective review of approximately 200 patients with a diagnosis of exudative macular degeneration treated with triple combination therapy (Bevacizumab, Dexamethasone and Photo-dynamic therapy) during the years of 2006 to 2010 at The Retina Center and compare those results with an additional group of approximately 200 patients also treated with triple combination therapy and 20 mg of daily oral zeaxanthin.

Detailed Description

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Study parameters will include best corrected visual acuity, number of combination treatments, reduction of central foveal thickness by OCT measurement and development of exudative macular degeneration in the fellow eye. Follow up will include all patients with a minimum of two years. Retrospective review of patient charts in the office of The Retina Center.

Conditions

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Exudative Macular Degeneration

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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2006 TO 2010 PATIENTS

PATIENTS TREATED WITH TRIPLE COMBINATION THERAPY

TRIPLE COMBINATION THERAPY

Intervention Type PROCEDURE

TREATMENT WITH BEVACIZUMAB, DEXAMETHASONE AND PHOTODYNAMIC THERAPY

CURRENT PATIENTS

PATIENTS TREATED WITH TRIPLE COMBINATION THERAPY AND ADDITION OF 20 MG OF ORAL ZEAXANTHIN

TRIPLE COMBINATION THERAPY

Intervention Type PROCEDURE

TREATMENT WITH BEVACIZUMAB, DEXAMETHASONE AND PHOTODYNAMIC THERAPY

Interventions

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TRIPLE COMBINATION THERAPY

TREATMENT WITH BEVACIZUMAB, DEXAMETHASONE AND PHOTODYNAMIC THERAPY

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

\- MUST HAVE AGE RELATED MACULAR DEGENERATION

Exclusion Criteria

\-
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Retina Center of St. Louis County, PC

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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ROBERT J OLK, MD

Role: PRINCIPAL_INVESTIGATOR

THE RETINA CENTER

Locations

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The Retina Center

St Louis, Missouri, United States

Site Status

Countries

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United States

Other Identifiers

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14-07-0540

Identifier Type: -

Identifier Source: org_study_id

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