Effect of Functional Electrical Stimulation on Erectile Dysfunction

NCT ID: NCT02284659

Last Updated: 2015-03-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-11-30

Study Completion Date

2015-03-31

Brief Summary

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Objective: The aim of this study is to evaluate the FES effect on erectile function in men with erectile dysfunction.

Expected Results: The hypothesis is that treatment with FES decrease erectile dysfunction.

Detailed Description

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Introduction: Erectile dysfunction (ED) affects approximately 150 million men worldwide. The application of functional electrical stimulation (FES) has been used due to the high regenerative capacity of smooth muscle cells. This approach can be beneficial in the treatment of which usually has the ultimate causes cavernous smooth muscle degeneration.

Objective: The aim of this study is to evaluate the FES effect on erectile function in men with erectile dysfunction.

Methods: Randomized Clinical Trial will be selected in which 30 patients with erectile dysfunction. The men included will be randomized into two groups. The intervention group will conduct therapy with FES (50Hz / 500us) for 15 minutes with intensity below the motor threshold and the control group will use FES placebo. Two sessions will be held weekly for four weeks. Erectile function will be assessed using the validated questionnaire IIEF-5. The instrument will be completed by blinded researcher and the technique is randomized and the treatment done randomly.

Expected Results: The hypothesis is that treatment with FES decrease erectile dysfunction.

Conditions

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Erectile Dysfunction

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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FES-sham

Functional Electro Stimulation (FES-sham)

Group Type SHAM_COMPARATOR

FES- Sham

Intervention Type DEVICE

Intervention (FES)

functional electro stimulation

Group Type ACTIVE_COMPARATOR

Functional Electrical Stimulation (FES)

Intervention Type DEVICE

FES (50Hz / 500us)

Interventions

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Functional Electrical Stimulation (FES)

FES (50Hz / 500us)

Intervention Type DEVICE

FES- Sham

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Male patient
* 40 to 65 years of age, with stable marital relationship (6 months)
* Diagnosis of erectile dysfunction (score of less than 22 IIEF5)
* Clinical history of ED for at least 6 months

Exclusion Criteria

* A neurogenic (spinal cord injury, Parkinson's, MS, post prostatectomy)
* Hypogonadism (total testosterone \<300 ng / dl)
* Patient reporting use of inhibitors or 5PDE FIC in the last 60 days
* Diagnosis of coronary artery disease and / or cerebrovascular disease
* Impossibility of understanding the goals, technical study and informed consent cognitive impairment
Minimum Eligible Age

40 Years

Maximum Eligible Age

70 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Federal University of Health Science of Porto Alegre

OTHER

Sponsor Role lead

Responsible Party

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Cristiane Carboni

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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FUHSPortoAlegre

Identifier Type: -

Identifier Source: org_study_id

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