Dexmedetomidine Adjuvant in Retinal Surgery

NCT ID: NCT02282787

Last Updated: 2015-03-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE3

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-01-31

Study Completion Date

2015-05-31

Brief Summary

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During LA in retinal surgery there is some problem as regard the lack of anaesthesia duration and unexpected globe movement .so many adjuvant was added to LA to overcome this disadvantages of LA such as clonidine and fentanyl .

The investigators hypothesis is adding dexmedetomidine to pribulbal blocking LA will prolong anaesthesia duration and improve globe akinesia and decrease intraoperative supplementation of LA.There are Many studies had described the effects of dexmedetomidine on peripheral nerve blocks, spinal but up to date no knowledge is available on the impact of dexmedetomidine adjuvant to local anaesthetic in ophthalmic surgery

Detailed Description

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Conditions

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Peribulbar Anesthesia

Keywords

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local anesthesia peribulbar anesthesia DEXMEDETOMIDINE vitreoretinal surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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5 micron dex arm

Group Type EXPERIMENTAL

DEXMEDETOMIDINE

Intervention Type DRUG

Does adding 5 or 10 micron of DEXMEDETOMIDINE to peribulbar anesthesia is any different from regular peribulbar anesthesia practice?

10 micron dex arm

Group Type EXPERIMENTAL

DEXMEDETOMIDINE

Intervention Type DRUG

Does adding 5 or 10 micron of DEXMEDETOMIDINE to peribulbar anesthesia is any different from regular peribulbar anesthesia practice?

Interventions

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DEXMEDETOMIDINE

Does adding 5 or 10 micron of DEXMEDETOMIDINE to peribulbar anesthesia is any different from regular peribulbar anesthesia practice?

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Adult patients
* Going for elective vitreoretinal surgery.

Exclusion Criteria

* History of coagulation abnormalities.
* Allergy to local anesthetics.
* Cardiac, hepatic or renal failure,
* Chronic clonidine or analgesic therapy.
* One-eyed patients
Minimum Eligible Age

40 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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King Saud University

OTHER

Sponsor Role lead

Responsible Party

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Marwan Abouammoh

Associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Marwan Abouammoh, MD

Role: PRINCIPAL_INVESTIGATOR

King Saud University

Locations

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King Abdulaziz University Hospital at King Saud University

Riyadh, Riyadh Region, Saudi Arabia

Site Status

Countries

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Saudi Arabia

Other Identifiers

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E-14-1291

Identifier Type: -

Identifier Source: org_study_id