Ultrasound Guided Thoracic Paravertebral Block for Hepatic Tumors Ablation

NCT ID: NCT02271646

Last Updated: 2019-03-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

35 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-08-31

Study Completion Date

2015-03-31

Brief Summary

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Patients undergo percutaneous radiofrequency ablation of hepatic tumors at Siriraj hospital normally receive only intravenous sedative drugs which sometimes can not provide effective pain control.

TPVB is suitable for unilateral operations. And it is increasing popular nowadays because of using ultrasound guided which make it is more reliable and has less side effects especially the severe one such as pneumothorax. To cover all nerve supply liver, we decided to use right TPVB at T5-6, T7-8, and T9-10.

The aim of this study is to prove that TPVB can provide an effective pain control for patients undergo liver RFA both at rest and movement (cough). We are going to measure the pain score at recovery room and the effective pain control means patients has mild pain (pain score less \</= 3 and do not ask for analgesic drugs).

Detailed Description

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Conditions

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Liver Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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0.5% marcaine 20ml

3 levels ultrasound guided thoracic paravertebral blocks at T5-6, T7-8 and T9-10 (total 0.5% marcaine 20ml)

Group Type EXPERIMENTAL

0.5% marcaine 20ml

Intervention Type DRUG

3 levels ultrasound guided thoracic paravertebral block at T5-6, T7-8 and T9-10 (total 0.5% marcaine 20ml)

Interventions

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0.5% marcaine 20ml

3 levels ultrasound guided thoracic paravertebral block at T5-6, T7-8 and T9-10 (total 0.5% marcaine 20ml)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Age \> 18 years
* Patients undergo percutaneous radiofrequency ablation for liver tumors
* ASA classification 1-3

Exclusion Criteria

* Psychiatric illness
* Chronic abdominal pain \> 1 week
* Regular analgesic drugs use
* Infection at back (Block area)
* Severe spinal deformity
* PT \> 16 sec, aPTT \> 32, platelet \< 50,000/cumm
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Siriraj Hospital

OTHER

Sponsor Role collaborator

Mahidol University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pawinee Pangthipampai, M.D.

Role: PRINCIPAL_INVESTIGATOR

Mahidol University

Locations

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Siriraj hospital

Bangkok, , Thailand

Site Status

Countries

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Thailand

Other Identifiers

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(IO) R015731063

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

070/2557(EC2)

Identifier Type: -

Identifier Source: org_study_id

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