Hyperglycemia and Effects of Daily 100 mg Versus 200 mg of Hydrocortisone Therapy in Patients With Septic Shock
NCT ID: NCT02266264
Last Updated: 2017-10-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
80 participants
INTERVENTIONAL
2014-10-31
2017-05-31
Brief Summary
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Detailed Description
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Also, 28-day mortality will be follow after hydrocortisone is started.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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100 milligrams of hydrocortisone
100 milligrams per day of hydrocortisone is the starting dosage.
Hydrocortisone
Subjects will be divided into two groups by randomization. The intervention-group will be received 100 milligrams per day of hydrocortisone and the control-group will be received 200 milligrams per day of hydrocortisone in the first three days after enrollment.
200 milligrams of hydrocortisone
200 milligrams per day of hydrocortisone is the starting dosage.
Hydrocortisone
Subjects will be divided into two groups by randomization. The intervention-group will be received 100 milligrams per day of hydrocortisone and the control-group will be received 200 milligrams per day of hydrocortisone in the first three days after enrollment.
Interventions
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Hydrocortisone
Subjects will be divided into two groups by randomization. The intervention-group will be received 100 milligrams per day of hydrocortisone and the control-group will be received 200 milligrams per day of hydrocortisone in the first three days after enrollment.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Adequate fluid resuscitation and vasopressor therapy are unable to maintain hemodynamic stability
Exclusion Criteria
* Established adrenal insufficiency
* Currently used in chemotherapy or immunosuppressive agents
* Radiotherapy currently received
* Known HIV infection
* Pregnancy
18 Years
ALL
No
Sponsors
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Srinakharinwirot University
OTHER
Responsible Party
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Kanchana Ngaosuwan
Doctor
Principal Investigators
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Kanchana Ngaosuwan, Master
Role: PRINCIPAL_INVESTIGATOR
Department of Medicine, Faculty of Medicine, Srinakharinwirot University
Locations
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Department of Medicine, Faculty of Medicine, Srinakharinwirot University
Ongkharak, Changwat Nakhon Nayok, Thailand
Countries
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Other Identifiers
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MED-R2R-200
Identifier Type: -
Identifier Source: org_study_id