A Prospective Study on USS Assessment of Pelvic Structures in 3rd Trimester of Pregnancy Versus Delivery Outcome

NCT ID: NCT02265081

Last Updated: 2015-07-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

135 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-11-30

Study Completion Date

2015-07-31

Brief Summary

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The proposed study is to evaluate if there are specific factors in the pelvic floor functional anatomy which can predict the ability of having a vaginal birth after caesarean section.

Physical characteristics of the soft tissue in the female pelvis play an important role in successful vaginal delivery. A "tight" or less distensible pelvic floor muscles may influence mode of delivery, leading to poor labour progression and by compressing foetal head produce CTG abnormality such as decelerations, both resulting in caesarean delivery.

One of the main structures of the pelvic floor, the puborectoalis muscle, facilitates the passage of fetal head through the birth canal by stretching and distending. Therefore distensibility of the female pelvic floor influences mode of delivery.

Three hundred patients, in the third trimester of pregnancy, will be recruited via the antenatal clinics to minimize any disruption in their pregnancy care provision. Eligible participants are pregnant women who had either one or no vaginal births, or one caesarean section and who can give an informed consent and maintain their autonomy regarding mode of delivery with understanding of the forthcoming study results. Participants will be excluded if they sustain any obstetric complications that may impede on time and mode of delivery including an emergency prelabour caesarean section.

Ultrasonographic assessment of the differences in the pelvic characteristics of these women will be used to predict a successful of trial of vaginal delivery after caesarean section (VBAC) in subsequent pregnancies. The results will be used to better inform whether there is a simple (single ultrasound assessment) that can be used to help inform women's choice regarding mode of delivery.

Results from this research could be a pioneering blueprint for further studies, as there is very little known about this topic.

Detailed Description

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Conditions

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Pelvic Floor Disorders Pregnancy

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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nulliparous women

internal ultrasound in the 3rd trimester uroflow meter in 3rd trimester

Group Type ACTIVE_COMPARATOR

ultrasound

Intervention Type PROCEDURE

pelvic floor ultrasound

uroflow-meter

Intervention Type PROCEDURE

uroflow meter: measurement of passed urine volume

parous women

those who had vaginal delivery in the past; internal ultrasound in the 3rd trimester uroflow meter in 3rd trimester

Group Type EXPERIMENTAL

ultrasound

Intervention Type PROCEDURE

pelvic floor ultrasound

uroflow-meter

Intervention Type PROCEDURE

uroflow meter: measurement of passed urine volume

parous women - VBAC

those with previous LSCS and no vaginal births; internal ultrasound in the 3rd trimester uroflow meter in 3rd trimester

Group Type EXPERIMENTAL

ultrasound

Intervention Type PROCEDURE

pelvic floor ultrasound

uroflow-meter

Intervention Type PROCEDURE

uroflow meter: measurement of passed urine volume

Interventions

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ultrasound

pelvic floor ultrasound

Intervention Type PROCEDURE

uroflow-meter

uroflow meter: measurement of passed urine volume

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. English speaking women
2. over 16 years old women
3. women willing to provide written informed consent
4. women who had either prior vaginal delivery or caesarean section or no prior birth experience

Exclusion Criteria

1. Women who cannot give an informed consent,
2. under the age of consent,
3. any participants whose pregnancies complicated during the antenatal period that may influence decision on time and mode of delivery that is anyone who has to undergo an emergency prelabour LSCS,
4. nonEnglish speaking women
5. less than 16 years old women
Minimum Eligible Age

16 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Birmingham Women's NHS Foundation Trust

OTHER_GOV

Sponsor Role lead

Responsible Party

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Aneta Obloza

DR ANETA OBLOZA

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kelly Hard

Role: STUDY_CHAIR

R&D Dept, Birmingham Women's Hospital, UK

Locations

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Birmingham Women's Hospital

Birmingham, , United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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U1111-1162-7720

Identifier Type: -

Identifier Source: org_study_id

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