Appropriated Bowel Preparation Before Exploratory Laparotomy in Gynecologic Surgery

NCT ID: NCT02263443

Last Updated: 2015-11-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

330 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-10-31

Study Completion Date

2015-11-30

Brief Summary

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Our study perform In Department of Gynecology, Faculty of Medicine, Chiang Mai University. In our study we divide patients into 3 groups ,First group patients doing Soap suds enema (S.S.E.), second group patients doing sodium chloride enema and the last group patient Non per os (NPO) before surgery. Our hypothesis is no different about surgical view in 3 groups and lower side effects in patients in no bowel preparation group.

Research objectives

1. Comparing the surgeon satisfaction ,surgical view and bowel handling in operation of soap suds enema group, sodium chloride enema group and the NPO group in patients under going exploratory laparotomy in gynecologic surgery.
2. Comparing the side effects of soap suds enema group, sodium chloride enema group and the NPO group.

Inclusion Criteria

1\. Women under going laparotomy in gynecologic surgery 2. Surgeon consider not too difficult surgery. 3. Can understanding Thai language. 4. Can communicate with researcher. 5. Consenting participants. Exclusion Criteria

1. Pregnancy or suspected pregnancy.
2. Laparoscopic surgery
3. Do not consent to participate in research
4. Gastrointestinal infection
5. Underlying disease such as Intestinal disease, patient who cannot under going bowel preparation ,heart disease ,seizure.
6. Surgeon consider difficult surgery such as fixed mass or uterus with others organs from per vaginal examination or very huge mass or history of difficult surgery or history of severe adhesion in abdominal cavity.

Detailed Description

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Methods

1. Divide patients into 3 groups ,First group patients doing Soap suds enema (S.S.E.), second group patients doing sodium chloride enema and the last group patient Non per os (NPO) before surgery
2. Patients information such as age, height, weight, smoking, history of surgery, number of surgeries, diagnosis that required surgery. The complete blood count and the laboratory prior to surgery record by the research team.
3. Patients do self questionnaire about symptoms such as abdominal pain or discomfort , anxiety ,nausea and vomiting etc. these are for understanding symptoms of patients before bowel preparation perform.
4. Computer-generated sequence into block for 30 person
5. Random into 3 groups by nurses .in opaque envelopes with number infront of to identify patients. Surgeon must not know what group of these patients get in.
6. Patients in S.S.E. group will bowel preparation by soap suds enema until clear at night before surgery.
7. Patients in unison enema group will Unison enema 100 ml per rectal at night before surgery
8. Patients NPO groups will NPO and no bowel preparation.
9. Patients in all group are doing operative preparation such as NPO after midnight, retained foley catheter and clean abdomen and perineum before surgery. Closs matching blood.
10. In the morning before surgery , patients do self questionnaire about symptoms score such as abdominal pain or discomfort , anxiety ,nausea and vomiting etc. for symptoms of patients after bowel preparation perform last night.
11. In operation room , surgeon evaluate surgical view, bowel handling after use swabs for bowel packing and record by nurse and after operation finish surgeon evaluate satisfaction of operation.
12. One day after surgery and before discharge from hospital patients do self questionnaire about symptoms score such as abdominal pain or discomfort , anxiety ,nausea and vomiting etc

Conditions

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Cathartic Colon Other Surgical Procedures

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

SINGLE

Caregivers

Study Groups

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Soap sus enema (S.S.E.)

Patients in S.S.E. group will receive bowel preparation by soap suds enema until clear at night before surgery.

Group Type EXPERIMENTAL

Soap suds enema (S.S.E.)

Intervention Type PROCEDURE

Patients in S.S.E. group will bowel preparation by soap suds enema until clear at night before surgery.

sodium chloride enema

Patients in unison enema group will receive Unison enema 100 ml per rectal at night before surgery.

Group Type EXPERIMENTAL

sodium chloride enema

Intervention Type PROCEDURE

Patients in unison enema group will Unison enema 100 ml per rectal at night before surgery

no enema

Patients will receive none of bowel preparation. NPO after midnight

Group Type PLACEBO_COMPARATOR

No enema

Intervention Type PROCEDURE

Patients NPO groups will NPO and no bowel preparation.

Interventions

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Soap suds enema (S.S.E.)

Patients in S.S.E. group will bowel preparation by soap suds enema until clear at night before surgery.

Intervention Type PROCEDURE

sodium chloride enema

Patients in unison enema group will Unison enema 100 ml per rectal at night before surgery

Intervention Type PROCEDURE

No enema

Patients NPO groups will NPO and no bowel preparation.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. Women under going laparotomy in gynecologic surgery
2. Surgeon consider not too difficult surgery.
3. Can understanding Thai language.
4. Can communicate with researcher.
5. Consenting participants.

Exclusion Criteria

1. Pregnancy or suspected pregnancy.
2. Laparoscopic surgery
3. Do not consent to participate in research
4. Gastrointestinal infection
5. Underlying disease such as Intestinal disease, patient who cannot under going bowel preparation ,heart disease ,seizure.
6. Surgeon consider difficult surgery such as fixed mass or uterus with others organs from per vaginal examination or very huge mass or history of difficult surgery or history of severe adhesion in abdominal cavity.
Maximum Eligible Age

80 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Prapaporn Suprasert

UNKNOWN

Sponsor Role collaborator

Chiang Mai University

OTHER

Sponsor Role lead

Responsible Party

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Wasakorn Suadee

M.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Prapaporn - Suprasert

Role: STUDY_DIRECTOR

Chiang Mai University

Locations

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Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University

Amphoe Muang, Chiang Mai, Thailand

Site Status

Countries

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Thailand

Other Identifiers

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OBG-2557-02203

Identifier Type: -

Identifier Source: org_study_id