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Anaerobic Power and Salbutamol

NCT ID: NCT02255630

Last Updated: 2016-11-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-01-31

Study Completion Date

2016-08-31

Brief Summary

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Athletes using inhaled β2-adrenoreceptor agonists (IBAs) win a disproportionate number of medals. However, most previous research has shown that β2 agonists do not improve exercise performance in either asthmatic or non-asthmatic athletes. Although the majority of these studies do not show an ergogenic effect, the small number of studies with extended exercise bouts (\~60 minutes) do show an advantage. The investigators believe that a controlled yet sport-specific exercise protocol will elucidate this ergogenic effect. Because IBAs may have different effects on these two groups of athletes, the investigators will measure exercise performance in both female and male elite cyclists. The investigators hypothesize that athletes will perform better during a combination steady-state/sprint exercise task following salbutamol administration.

Detailed Description

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Conditions

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Ergogenic Athletic Performance

Keywords

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salbutamol exercise-induced bronchoconstriction anaerobic power

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Salbutamol inhalation

Study participants will be exposed to 1600ug salbutamol 30min prior to exercise

Group Type EXPERIMENTAL

Cycling Exercise

Intervention Type OTHER

Placebo inhalation

Study participants will be exposed to 1600ug salbutamol 30min prior to exercise

Group Type EXPERIMENTAL

Cycling Exercise

Intervention Type OTHER

Interventions

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Cycling Exercise

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* maximal oxygen consumption of ≥60 and ≥55 mL⋅kg-1⋅min-1 or ≥5⋅L⋅min-1 and ≥4⋅L⋅min-1 for men and women

Exclusion Criteria

* pregnant women
* any history of uncontrolled respiratory or cardiac disease
* smokers
* diabetics
Minimum Eligible Age

19 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Natural Sciences and Engineering Research Council, Canada

OTHER

Sponsor Role collaborator

University of British Columbia

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michael S Koehle, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University of British Columbia

Locations

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University of British Columbia, Environmental Physiology Laboratory

Vancouver, British Columbia, Canada

Site Status

Countries

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Canada

Other Identifiers

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H14-02788

Identifier Type: -

Identifier Source: org_study_id