Thrombolytic Therapy Versus Surgery for Obstructive Prosthetic Valve Thrombosis
NCT ID: NCT02243839
Last Updated: 2014-09-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
100 participants
INTERVENTIONAL
2014-01-31
2015-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Thrombolytic therapy
In the first arm, thrombolytic therapy (TT) is performed to the patients with obstructive prosthetic valve thrombosis. The TT regimen depends on the functional status of the patient. In patients with NYHA class III-IV dyspnea low dose, relatively faster TT regimen (25 mg tPA/6 hours) is performed. In patients with NYHA class I-II dyspnea TT with low dose and ultra-slow infusion of tPA (25 mg tPA/25 hours) is performed. During TT, patients are followed up with transesophageal echocardiography in every 24 hours.
Thrombolytic Therapy
Thrombolytic therapy is performed to the patients with obstructive prosthetic valve thrombosis
Surgery
In the second arm, redo valve surgery is performed for obstructive valve thrombosis. Intraoperative and postoperative results are recorded
Surgery
Redo valve surgery is performed for obstructive valve thrombosis
Interventions
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Thrombolytic Therapy
Thrombolytic therapy is performed to the patients with obstructive prosthetic valve thrombosis
Surgery
Redo valve surgery is performed for obstructive valve thrombosis
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
85 Years
ALL
No
Sponsors
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Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
OTHER_GOV
Responsible Party
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MEHMET OZKAN
Professor
Locations
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Kosuyolu Kartal Heart Training and Research Hospital
Istanbul, , Turkey (Türkiye)
Countries
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Facility Contacts
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Other Identifiers
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KOSUYOLU3
Identifier Type: -
Identifier Source: org_study_id
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