The Use of Pramipexole and Other Dopamine Agonists and the Risks of Heart Failure and Pneumonia

NCT ID: NCT02236741

Last Updated: 2014-09-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

26814 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-11-30

Brief Summary

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Study to assess the risk of incident heart failure associated with the use of pramipexole compared with other dopamine agonists and additionally, to assess the risk of incident heart failure associated with the use of dopamine agonists in comparison with no use of dopamine agonist therapy

Detailed Description

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Conditions

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Heart Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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users of anti-parkinsonian drugs

Mirapexin® (Sifrol®)

Intervention Type DRUG

Interventions

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Mirapexin® (Sifrol®)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* All patients between 40 and 89 years of age who received at least one prescription for anti-parkinsonian drugs during the period 1997-2009

Exclusion Criteria

* Patients with a diagnosis of heart failure or with prescriptions for two or more among the digitalis, angiotensin-converting enzyme (ACE) inhibitors/angiotensin receptor blocker (ARB), and diuretic drug classes prior to cohort entry
Minimum Eligible Age

40 Years

Maximum Eligible Age

89 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Boehringer Ingelheim

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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248.672

Identifier Type: -

Identifier Source: org_study_id

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