Trial Outcomes & Findings for Cryo Balloon for Residual Barrett's Esophagus (NCT NCT02230410)

NCT ID: NCT02230410

Last Updated: 2022-02-10

Results Overview

Number of subjects to have eradication of barrett's esophagus after Cryoballoon Focal Ablation

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

18 participants

Primary outcome timeframe

3 months post Cryoballon Focal Ablation

Results posted on

2022-02-10

Participant Flow

Participant milestones

Participant milestones
Measure
Focal Cryo Ablation
Subjects with residual barrett's esophagus (less than 3 cm) post ablation will under go one CryoBalloon Focal Ablation treatment CryoBalloon Focal Ablation
Overall Study
STARTED
18
Overall Study
COMPLETED
15
Overall Study
NOT COMPLETED
3

Reasons for withdrawal

Reasons for withdrawal
Measure
Focal Cryo Ablation
Subjects with residual barrett's esophagus (less than 3 cm) post ablation will under go one CryoBalloon Focal Ablation treatment CryoBalloon Focal Ablation
Overall Study
Screen Failure
3

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Focal Cryo Ablation
n=18 Participants
Subjects with residual barrett's esophagus (less than 3 cm) post ablation will under go one CryoBalloon Focal Ablation treatment CryoBalloon Focal Ablation
Age, Continuous
67.94 years
STANDARD_DEVIATION 7.99 • n=18 Participants
Sex: Female, Male
Female
2 Participants
n=18 Participants
Sex: Female, Male
Male
16 Participants
n=18 Participants
Region of Enrollment
United States
18 participants
n=18 Participants

PRIMARY outcome

Timeframe: 3 months post Cryoballon Focal Ablation

Number of subjects to have eradication of barrett's esophagus after Cryoballoon Focal Ablation

Outcome measures

Outcome measures
Measure
Focal Cryo Ablation
n=15 Participants
Subjects with residual barrett's esophagus (less than 3 cm) post ablation will under go one CryoBalloon Focal Ablation treatment CryoBalloon Focal Ablation
Eradication of Barrett's Esophagus
2 Participants

Adverse Events

Focal Cryo Ablation

Serious events: 0 serious events
Other events: 1 other events
Deaths: 1 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
Focal Cryo Ablation
n=18 participants at risk
Subjects with residual barrett's esophagus (less than 3 cm) post ablation will under go one CryoBalloon Focal Ablation treatment CryoBalloon Focal Ablation
Gastrointestinal disorders
Difficulty Swallowing
5.6%
1/18 • Adverse events were collected from baseline to end of study for a total of approximately 3 months on all participants.

Additional Information

Dr. Kenneth K. Wang

Mayo Clinic

Phone: 507-293-7911

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place