Evaluating the Effectiveness of Neupro® (Rotigotine) and L-dopa Combination Therapy in Patients With Parkinson's Disease

NCT ID: NCT02227355

Last Updated: 2016-07-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

195 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-09-30

Study Completion Date

2016-06-30

Brief Summary

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This study aims to evaluate the effectiveness of Rotigotine and Levodopa combination therapy for younger and older patients with Parkinson's Disease under real life conditions. Effects on ability to perform activities of daily living, sleep, medication dose and other factors will be assessed.

Detailed Description

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Conditions

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Idiopathic Parkinson's Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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PD Patients < 70 years of age

Patients with Parkinson's Disease (PD) \<70 years of age.

No interventions assigned to this group

PD Patients ≥ 70 years of age

Patients with Parkinson's Disease (PD) ≥ 70 years of age.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

The following selection criteria must be followed for patients entering the Noninterventional Study (NIS):

* The decision by the treating physician to prescribe Rotigotine transdermal patch is made before participating in the NIS due to a clinical therapeutic indication (e.g., because of intolerance and/or ineffectiveness of another dopamine agonist)
* The patient is either male or female and over 18 years of age
* A Patient Data Consent form is signed and dated by the patient or by the legal representative
* The patient has idiopathic Parkinson's Disease, has not received Rotigotine within 28 days prior to the Baseline Visit and is willing to participate in questionnaire based assessments
* The patient is receiving L-dopa as monotherapy or a combination therapy composed of L-dopa and a dopamine agonist other than Rotigotine
* The patient has been on L-dopa therapy for at least 6 months and is responding to initial L-dopa therapy
* The patient has a Hoehn and Yahr stage score of 1 to 4.

Exclusion Criteria

* Patients will be excluded from the study if they have participated in a clinical study of a medication or a medical device within 3 months prior to Baseline or if they are participating in a clinical study at the time of inclusion or have already participated in the current study.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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PRA Health Sciences

INDUSTRY

Sponsor Role collaborator

UCB Biopharma S.P.R.L.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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UCB Clinical Trial Call Center

Role: STUDY_DIRECTOR

+1 877 822 9493 (UCB)

Locations

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42

Lille, , France

Site Status

41

Mougins, , France

Site Status

40

Nîmes, , France

Site Status

6

Alzenau in Unterfranken, , Germany

Site Status

51

Aschaffenburg, , Germany

Site Status

13

Beelitz-Heilstätten, , Germany

Site Status

12

Berlin, , Germany

Site Status

5

Böblingen, , Germany

Site Status

53

Düsseldorf, , Germany

Site Status

7

Erbach im Odenwald, , Germany

Site Status

4

Haag, , Germany

Site Status

11

Leer, , Germany

Site Status

2

Münster, , Germany

Site Status

54

Schriesheim, , Germany

Site Status

8

Senftenberg, , Germany

Site Status

14

Tübingen, , Germany

Site Status

10

Ulm, , Germany

Site Status

3

Westerstede, , Germany

Site Status

45

Ancona, , Italy

Site Status

47

Brescia, , Italy

Site Status

60

Cagliari, , Italy

Site Status

29

Cosenza, , Italy

Site Status

30

Florence, , Italy

Site Status

46

Milan, , Italy

Site Status

27

Napoli, , Italy

Site Status

28

Roma, , Italy

Site Status

62

Roma, , Italy

Site Status

20

Barakaldo, , Spain

Site Status

15

Donostia / San Sebastian, , Spain

Site Status

24

Madrid, , Spain

Site Status

22

Palma de Mallorca, , Spain

Site Status

37

Bury, , United Kingdom

Site Status

49

Cambridge, , United Kingdom

Site Status

52

Lincoln, , United Kingdom

Site Status

48

Liverpool, , United Kingdom

Site Status

33

London, , United Kingdom

Site Status

36

London, , United Kingdom

Site Status

34

Manchester, , United Kingdom

Site Status

31

Middlesbrough, , United Kingdom

Site Status

38

North Shields, , United Kingdom

Site Status

35

Norwich, , United Kingdom

Site Status

63

Plymouth, , United Kingdom

Site Status

Countries

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France Germany Italy Spain United Kingdom

Other Identifiers

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PD0013

Identifier Type: -

Identifier Source: org_study_id

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