Interaction of Statins and Nondepolarizing Muscle Relaxants

NCT ID: NCT02222519

Last Updated: 2014-10-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-10-31

Study Completion Date

2015-09-30

Brief Summary

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provide evidence for prevention or reduction muscle pain.

Detailed Description

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The purpose of this study is to determine interaction of statins and nondepolarizing muscle relaxant,In order to provide evidence for prevention or reduction muscle pain.

Conditions

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Pain

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Statin use group

patients taking statins for at least 3 months

Rocuronium

Intervention Type DRUG

Rocuronium 0.6mg/kg iv single dose

non statin use

no history of taking statin

Rocuronium

Intervention Type DRUG

Rocuronium 0.6mg/kg iv single dose

Interventions

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Rocuronium

Rocuronium 0.6mg/kg iv single dose

Intervention Type DRUG

Other Intervention Names

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Rocuronium Bromide Injection Esmeron http://www.msdchina.com.cn/

Eligibility Criteria

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Inclusion Criteria

* Patients with American Society of Anesthesiologists physical status I-III
* Patients taking statins for at least 3 months and those who had never used statins were considered to be eligible

Exclusion Criteria

* Orthopedic
* Spinal surgery
* Surgery involving extensive muscle manipulation
* History of liver and kidney failure
* Neuromuscular disease
* Susceptibility to or family history of malignant hyperthermia
* Extensive denervation of skeletal muscle
* Chronic pain syndromes
* Taking medications that might interact with the effect of rocuronium or serum myoglobin difficult intubation
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Huang-wei LV

OTHER

Sponsor Role lead

Responsible Party

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Huang-wei LV

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Huangwei Lv, Professor

Role: STUDY_DIRECTOR

the Anesthesiology Department

Locations

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China Medical University

Shenyang, Liaoning, China

Site Status RECRUITING

Countries

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China

Facility Contacts

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Huang-wei Lv, Professor

Role: primary

86-024-83283100

Other Identifiers

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2014071801

Identifier Type: -

Identifier Source: org_study_id

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