Early Waning of Maternal Measles and Meningitis C Antibodies

NCT ID: NCT02219061

Last Updated: 2014-09-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-05-31

Study Completion Date

2014-12-31

Brief Summary

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Maternal antibodies (measles and meningitis C) may wane in the first six months after birth.

* Geometric mean titers(GMTs) of measles and meningitis C.
* Follow-up on 0 month, 3rd month,5th month and 7th month after birth.

Detailed Description

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Measles and meningitis C are hot topics in China in recent years. Although China had set the goal of measles elimination, many measles cases were found to be those aged \< 8 months and meningitis C is becoming public health issue since meningitis group A has been controlled at a very low level and little is known on C group. So the investigators designed the observation study on the two antibodies.

Maternal antibodies are supposed to wane after birth. Serums of the placenta(0 month), children of 3 months, 5 months and 7 months old will be collected and the geometric mean titers (GMTs) of measles and meningitis C will be confirmed by using the ELISA test.

Conditions

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Measles

Study Design

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Study Time Perspective

PROSPECTIVE

Study Groups

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GMT

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Healthy infants.

Exclusion Criteria

* Infants with poor score.
Maximum Eligible Age

7 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Guangzhou Center for Disease Control and Prevention

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ming Wang

Role: PRINCIPAL_INVESTIGATOR

Guangzhou CDC

Locations

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Guangzhou Center for Disease Control and Prevention

Guangzhou, Guangdong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Chuanxi Fu, PhD

Role: CONTACT

+86 20 36055887

Facility Contacts

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Chuanxi

Role: primary

+86 20 36055887

Ming

Role: backup

Other Identifiers

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GZCDC001

Identifier Type: -

Identifier Source: org_study_id

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