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The Use of Angiotensin Recept...

The Use of Angiotensin Receptor Blockers and the Risk of Cancer

Last Updated: 2014-08-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1165781 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-02-28

Brief Summary

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The primary objective of this study was to assess whether angiotensin blockers (ARBs) and telmisartan in particular, are associated with an increased overall risk of the four most common cancers, namely, lung, colorectal, breast and prostate cancers. A secondary objective was to explore these effects separately for each of the four cancers and in combination with angiotensin-converting-enzyme-inhibitors (ACEIs).

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Detailed Description

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Conditions

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Neoplasm

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients prescribed antihypertensives

ARB

Intervention Type DRUG

other than telmisartan

ACEI

Intervention Type DRUG

Beta-blockers

Intervention Type DRUG

Diuretics

Intervention Type DRUG

Telmisartan

Intervention Type DRUG

Interventions

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ARB

other than telmisartan

Intervention Type DRUG

ACEI

Intervention Type DRUG

Beta-blockers

Intervention Type DRUG

Diuretics

Intervention Type DRUG

Telmisartan

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients prescribed an antihypertensive agent between 01-JAN-1995 and 31-DEC-2008 with at least two years of up-to-standard medical history in United Kingdom's General Practice Research Database (GPRD)