Trial Outcomes & Findings for Radiation Therapy vs. Observation Following Gemcitabine and Cisplatin for Inoperable Localized Liver Cancer (NCT NCT02200042)

NCT ID: NCT02200042

Last Updated: 2019-08-28

Results Overview

Overall survival time is defined as time from randomization to the date of death from any cause. Overall survival rates are estimated by the Kaplan-Meier method. Patients last known to be alive are censored at the date of last contact.

Recruitment status

TERMINATED

Study phase

PHASE3

Target enrollment

1 participants

Primary outcome timeframe

From randomization to last follow-up. Analysis occurs after all patients have been on study for at least two years.

Results posted on

2019-08-28

Participant Flow

Participant milestones

Participant milestones
Measure
Radiation Therapy
Liver-directed radiation therapy Radiation Therapy: Patients undergo 15 fractions of image-guided radiation therapy delivered over 19-26 or 27-34 days.
Observation
No radiation therapy
Overall Study
STARTED
0
1
Overall Study
COMPLETED
0
0
Overall Study
NOT COMPLETED
0
1

Reasons for withdrawal

Reasons for withdrawal
Measure
Radiation Therapy
Liver-directed radiation therapy Radiation Therapy: Patients undergo 15 fractions of image-guided radiation therapy delivered over 19-26 or 27-34 days.
Observation
No radiation therapy
Overall Study
Withdrawal by Subject
0
1

Baseline Characteristics

Radiation Therapy vs. Observation Following Gemcitabine and Cisplatin for Inoperable Localized Liver Cancer

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Radiation Therapy
Liver-directed radiation therapy Radiation Therapy: Patients undergo 15 fractions of image-guided radiation therapy delivered over 19-26 or 27-34 days.
Observation
n=1 Participants
No radiation therapy
Total
n=1 Participants
Total of all reporting groups
Age, Categorical
Between 18 and 65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
1 Participants
n=7 Participants
1 Participants
n=5 Participants
Sex: Female, Male
Female
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Sex: Female, Male
Male
0 Participants
n=5 Participants
1 Participants
n=7 Participants
1 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
0 Participants
n=5 Participants
1 Participants
n=7 Participants
1 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
White
0 Participants
n=5 Participants
1 Participants
n=7 Participants
1 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
<=18 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants

PRIMARY outcome

Timeframe: From randomization to last follow-up. Analysis occurs after all patients have been on study for at least two years.

Population: No patients have outcome data.

Overall survival time is defined as time from randomization to the date of death from any cause. Overall survival rates are estimated by the Kaplan-Meier method. Patients last known to be alive are censored at the date of last contact.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: From randomization to last follow-up. Analysis occurs after all patients have been on study for at least two years.

Population: No patients have outcome data.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: From randomization to last follow-up. Analysis occurs after all patients have been on study for at least two years.

Population: No patients have outcome data.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: From randomization to last follow-up. Analysis occurs after all patients have been on study for at least two years.

Population: No patients have outcome data.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: From randomization to last follow-up. Analysis occurs after all patients have been on study for at least two years.

Population: No patients have outcome data.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: From randomization to last follow-up. Analysis occurs after all patients have been on study for at least two years.

Population: No patients have outcome data.

Outcome measures

Outcome data not reported

Adverse Events

Radiation Therapy

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Observation

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Wendy Seiferheld

NRG Oncology

Phone: 215-574-3208

Results disclosure agreements

  • Principal investigator is a sponsor employee PI's are required to abide by the sponsor's publication guidelines which require review by coauthors and subsequent review and approval by the sponsor.
  • Publication restrictions are in place

Restriction type: OTHER