The Medacta International GMK Sphere Post-Marketing Surveillance Study

NCT ID: NCT02199600

Last Updated: 2024-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

500 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-10-31

Study Completion Date

2029-10-31

Brief Summary

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This is a Post-Marketing Surveillance of GMK Sphere knee prosthesis.

Detailed Description

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The clinical performance of the GMK® Sphere, manufactured by Medacta International, will be evaluated by a multicentre, prospective clinical surveillance study.

The Elective Orthopaedic Centre (EOC), in Epsom, Surrey, will be the study coordinating centre. Four further centres will participate in the clinical study, for five total centres. Each participating centre will recruit approximately 100 patients. Patient recruitment will cease when a cohort of 500 GMK® Sphere knee replacements have been implanted.

Conditions

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Arthritis Traumatic Arthritis Rheumatoid Arthritis Poly-arthritis Avascular Necrosis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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GMK Sphere Knee Replacement

Patients who comply with the protocol and received GMK Sphere component.

Group Type OTHER

GMK Sphere Knee Replacement

Intervention Type DEVICE

Interventions

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GMK Sphere Knee Replacement

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* A disabled or severely disabled joint as a result of arthritis, traumatic arthritis, rheumatoid arthritis, poly-arthritis or avascular necrosis
* Patients must be between the age of 18 and 80 at the time of consent
* Listed for total knee replacement surgery.
* Patients who are willing to give informed written consent

Exclusion Criteria

* Progressive local or systemic infection
* Muscular loss, neuromuscular disease or vascular deficiency of the affected limb, making the operation unjustifiable
* Severe instability secondary to advance destruction of condylar structures or loss of integrity of the medial or lateral ligament
* Any patient who cannot or will not provide informed consent for participation in the study
* Those whose prospects for a recovery to independent mobility would be compromised by known coexistent, medical problems
* Patient whose BMI exceeds 40
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medacta International SA

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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AZ Maria Middelares

Ghent, , Belgium

Site Status

Royal London Hospital

Whitechapel, London, United Kingdom

Site Status

Royal National Orthopaedic Hospital NHS Trust

Stanmore, Middlesex, United Kingdom

Site Status

The Elective Orthopaedic Centre (EOC)

Epsom, Surrey, United Kingdom

Site Status

Countries

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Belgium United Kingdom

Other Identifiers

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P02.014.01

Identifier Type: -

Identifier Source: org_study_id