Trial Outcomes & Findings for Physiotherapy in the Haemophilic Arthropathy of the Elbow. (NCT NCT02198040)
NCT ID: NCT02198040
Last Updated: 2018-03-01
Results Overview
Measurement the changes of flexion and extension of elbow (in degrees) using a universal goniometer. We were taken as anatomical references, those specified by Querol et al, using the zero-method-reference for the mobile arm goniometer as indicated Norkin et al.
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
27 participants
Primary outcome timeframe
Screening visit (pretreatment assessment), postreatment evaluation (12 week) and follow up assessment (6 months after treatment)
Results posted on
2018-03-01
Participant Flow
27 patients Hemophilia of the Association of Murcia were recruited between January to October 2013
28 patients who met the exclusion criteria. Only one declined to participate for personal reasons.
Participant milestones
| Measure |
Manual Therapy Group
The treatment of this group consisted of two sessions per week, one hour each. Manual Therapy: - 5 minutes. Termotherapy shalow to 50 cm away from the elbow, using a bulb of 250w.
* 15 minutes. Joint traction of elbow, in submaximal mobility amplitude with distal fixation of humerus and proximal fixation of radius and ulna in neutral position of forearm. Joint traction in I-II degree of flexion and extension submaximal of elbow.
* 15 minutes. Passive muscle stretching (within the limits of mobility). Compression technique, passive muscle stretching and relaxation in biceps and triceps.
* 15 minutes. Proprioceptive neuromuscular facilitation (PNF) of upper limb, from the abduction, flexion and external rotation of shoulder with extension of elbow and dorsal flexion of wrist, to adduction, internal rotation of shoulder with flexion of elbow and palmar flexion of wrist and fingers.
* 10
|
Educational Gruop
The treatment had education and home daily exercises for the improvement of the range of motion, biceps strength, perimeter of arm and the perception of pain in patients with haemophilia and arthropathy of the elbow.
Educational group: - Theory: Introduction to hemophilia: clinic and treatment; Anatomy and biomechanics of elbow; Anatomy of elbow musculature. Function of muscles and haematomas treatment; Haemarthrosis, synovitis and arthropathy: clinical manifestations and treatment; Proprioception: definition and importance in hemophilia; and Physical activity and sport: risks and benefits.
\- Practice: exercises in favor of gravity; isometric and isotonic exercises of elbow; active exercises for mobility and pain management; elbow proprioception exercises; and swimming technique.
|
Control Group
The control group did not receive any intervention. The patients in this group were assessed by the same reviewers (blinded to the study conditions) and under the same conditions, that patients in the experimental groups.
|
|---|---|---|---|
|
Overall Study
STARTED
|
9
|
9
|
9
|
|
Overall Study
COMPLETED
|
9
|
8
|
8
|
|
Overall Study
NOT COMPLETED
|
0
|
1
|
1
|
Reasons for withdrawal
| Measure |
Manual Therapy Group
The treatment of this group consisted of two sessions per week, one hour each. Manual Therapy: - 5 minutes. Termotherapy shalow to 50 cm away from the elbow, using a bulb of 250w.
* 15 minutes. Joint traction of elbow, in submaximal mobility amplitude with distal fixation of humerus and proximal fixation of radius and ulna in neutral position of forearm. Joint traction in I-II degree of flexion and extension submaximal of elbow.
* 15 minutes. Passive muscle stretching (within the limits of mobility). Compression technique, passive muscle stretching and relaxation in biceps and triceps.
* 15 minutes. Proprioceptive neuromuscular facilitation (PNF) of upper limb, from the abduction, flexion and external rotation of shoulder with extension of elbow and dorsal flexion of wrist, to adduction, internal rotation of shoulder with flexion of elbow and palmar flexion of wrist and fingers.
* 10
|
Educational Gruop
The treatment had education and home daily exercises for the improvement of the range of motion, biceps strength, perimeter of arm and the perception of pain in patients with haemophilia and arthropathy of the elbow.
Educational group: - Theory: Introduction to hemophilia: clinic and treatment; Anatomy and biomechanics of elbow; Anatomy of elbow musculature. Function of muscles and haematomas treatment; Haemarthrosis, synovitis and arthropathy: clinical manifestations and treatment; Proprioception: definition and importance in hemophilia; and Physical activity and sport: risks and benefits.
\- Practice: exercises in favor of gravity; isometric and isotonic exercises of elbow; active exercises for mobility and pain management; elbow proprioception exercises; and swimming technique.
|
Control Group
The control group did not receive any intervention. The patients in this group were assessed by the same reviewers (blinded to the study conditions) and under the same conditions, that patients in the experimental groups.
|
|---|---|---|---|
|
Overall Study
Work reasons
|
0
|
1
|
0
|
|
Overall Study
Withdrawal by Subject
|
0
|
0
|
1
|
Baseline Characteristics
Physiotherapy in the Haemophilic Arthropathy of the Elbow.
Baseline characteristics by cohort
| Measure |
Manual Therapy Group
n=9 Participants
The treatment of this group consisted of two sessions per week, one hour each.
Manual Therapy: - 5 minutes. Termotherapy shalow to 50 cm away from the elbow, using a bulb of 250w.
* 15 minutes. Joint traction of elbow, in submaximal mobility amplitude with distal fixation of humerus and proximal fixation of radius and ulna in neutral position of forearm. Joint traction in I-II degree of flexion and extension submaximal of elbow.
* 15 minutes. Passive muscle stretching (within the limits of mobility). Compression technique, passive muscle stretching and relaxation in biceps and triceps.
* 15 minutes. Proprioceptive neuromuscular facilitation (PNF) of upper limb, from the abduction, flexion and external rotation of shoulder with extension of elbow and dorsal flexion of wrist, to adduction, internal rotation of shoulder with flexion of elbow and palmar flexion of wrist and fingers.
* 10 minutes. Local cryotherapy with ice bag and protection between it and the skin
|
Educational Gruop
n=9 Participants
The treatment had education and home daily exercises for the improvement of the range of motion, biceps strength, perimeter of arm and the perception of pain in patients with haemophilia and arthropathy of the elbow.
Educational group: - Theory: Introduction to hemophilia: clinic and treatment; Anatomy and biomechanics of elbow; Anatomy of elbow musculature. Function of muscles and haematomas treatment; Haemarthrosis, synovitis and arthropathy: clinical manifestations and treatment; Proprioception: definition and importance in hemophilia; and Physical activity and sport: risks and benefits.
\- Practice: exercises in favor of gravity; isometric and isotonic exercises of elbow; active exercises for mobility and pain management; elbow proprioception exercises; and swimming technique.
|
Control Group
n=9 Participants
The control group did not receive any intervention. The patients in this group were assessed by the same reviewers (blinded to the study conditions) and under the same conditions, that patients in the experimental groups.
|
Total
n=27 Participants
Total of all reporting groups
|
|---|---|---|---|---|
|
Age, Categorical
<=18 years
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
0 Participants
n=4 Participants
|
|
Age, Categorical
Between 18 and 65 years
|
9 Participants
n=5 Participants
|
9 Participants
n=7 Participants
|
9 Participants
n=5 Participants
|
27 Participants
n=4 Participants
|
|
Age, Categorical
>=65 years
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
0 Participants
n=4 Participants
|
|
Sex: Female, Male
Female
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
0 Participants
n=4 Participants
|
|
Sex: Female, Male
Male
|
9 Participants
n=5 Participants
|
9 Participants
n=7 Participants
|
9 Participants
n=5 Participants
|
27 Participants
n=4 Participants
|
|
Region of Enrollment
Spain
|
9 participants
n=5 Participants
|
9 participants
n=7 Participants
|
9 participants
n=5 Participants
|
27 participants
n=4 Participants
|
|
Radiological joint deterioration
|
9.63 units on a scale
STANDARD_DEVIATION 1.62 • n=5 Participants
|
8.50 units on a scale
STANDARD_DEVIATION 3.40 • n=7 Participants
|
7.57 units on a scale
STANDARD_DEVIATION 2.90 • n=5 Participants
|
8.61 units on a scale
STANDARD_DEVIATION 2.809 • n=4 Participants
|
PRIMARY outcome
Timeframe: Screening visit (pretreatment assessment), postreatment evaluation (12 week) and follow up assessment (6 months after treatment)Population: It has made an analysis by intention to treat with the 27 patients included in the study.
Measurement the changes of flexion and extension of elbow (in degrees) using a universal goniometer. We were taken as anatomical references, those specified by Querol et al, using the zero-method-reference for the mobile arm goniometer as indicated Norkin et al.
Outcome measures
| Measure |
Educational Gruop
n=9 Participants
The treatment had education and home daily exercises for the improvement of the range of motion, biceps strength, perimeter of arm and the perception of pain in patients with haemophilia and arthropathy of the elbow.
Educational group: - Theory: Introduction to hemophilia: clinic and treatment; Anatomy and biomechanics of elbow; Anatomy of elbow musculature. Function of muscles and haematomas treatment; Haemarthrosis, synovitis and arthropathy: clinical manifestations and treatment; Proprioception: definition and importance in hemophilia; and Physical activity and sport: risks and benefits.
\- Practice: exercises in favor of gravity; isometric and isotonic exercises of elbow; active exercises for mobility and pain management; elbow proprioception exercises; and swimming technique.
|
Manual Therapy Group
n=9 Participants
The treatment of this group consisted of two sessions per week, one hour each. We used joint traction, passive muscles stretching and Proprioceptive Neuromuscular Facilitation
Manual Therapy: - 5 minutes. Termotherapy shalow to 50 cm away from the elbow, using a bulb of 250w.
* 15 minutes. Joint traction of elbow, in submaximal mobility amplitude with distal fixation of humerus and proximal fixation of radius and ulna in neutral position of forearm. Joint traction in I-II degree of flexion and extension submaximal of elbow.
* 15 minutes. Passive muscle stretching (within the limits of mobility). Compression technique, passive muscle stretching and relaxation in biceps and triceps.
* 15 minutes. Proprioceptive neuromuscular facilitation (PNF) of upper limb.
* 10 minutes. Local cryotherapy with ice bag and protection between it and the skin
|
Control Group
n=9 Participants
The control group did not receive any intervention. The patients in this group were assessed by the same reviewers (blinded to the study conditions) and under the same conditions, that patients in the experimental groups.
|
|---|---|---|---|
|
Changes in Range of Motion of Elbow
Pretreatment assessment
|
138.31 degrees
Standard Deviation 16.103
|
136.13 degrees
Standard Deviation 14.818
|
138.00 degrees
Standard Deviation 19.958
|
|
Changes in Range of Motion of Elbow
Postreatment assessment
|
135.56 degrees
Standard Deviation 16.66
|
140.31 degrees
Standard Deviation 11.24
|
138.43 degrees
Standard Deviation 18.47
|
|
Changes in Range of Motion of Elbow
Follow up assessment
|
139.19 degrees
Standard Deviation 16.64
|
140.31 degrees
Standard Deviation 14.44
|
138.07 degrees
Standard Deviation 17.39
|
PRIMARY outcome
Timeframe: Screening visit (pretreatment assessment), postreatment evaluation (12 week) and follow up assessment (6 months after treatment)Population: It has made an analysis by intention to treat with the 27 patients included in the study
Measurement of the arm circumference (in cm) at baseline as a result of hemophilic arthropathy and after treatment and follow-up. The measurement in the upper third of the arm, in the middle of the triceps muscle belly, with a tape measure. We use this outcome to measure circumference of the arm, it is the most clinical measurement used by physiotherapists.
Outcome measures
| Measure |
Educational Gruop
n=9 Participants
The treatment had education and home daily exercises for the improvement of the range of motion, biceps strength, perimeter of arm and the perception of pain in patients with haemophilia and arthropathy of the elbow.
Educational group: - Theory: Introduction to hemophilia: clinic and treatment; Anatomy and biomechanics of elbow; Anatomy of elbow musculature. Function of muscles and haematomas treatment; Haemarthrosis, synovitis and arthropathy: clinical manifestations and treatment; Proprioception: definition and importance in hemophilia; and Physical activity and sport: risks and benefits.
\- Practice: exercises in favor of gravity; isometric and isotonic exercises of elbow; active exercises for mobility and pain management; elbow proprioception exercises; and swimming technique.
|
Manual Therapy Group
n=9 Participants
The treatment of this group consisted of two sessions per week, one hour each. We used joint traction, passive muscles stretching and Proprioceptive Neuromuscular Facilitation
Manual Therapy: - 5 minutes. Termotherapy shalow to 50 cm away from the elbow, using a bulb of 250w.
* 15 minutes. Joint traction of elbow, in submaximal mobility amplitude with distal fixation of humerus and proximal fixation of radius and ulna in neutral position of forearm. Joint traction in I-II degree of flexion and extension submaximal of elbow.
* 15 minutes. Passive muscle stretching (within the limits of mobility). Compression technique, passive muscle stretching and relaxation in biceps and triceps.
* 15 minutes. Proprioceptive neuromuscular facilitation (PNF) of upper limb.
* 10 minutes. Local cryotherapy with ice bag and protection between it and the skin
|
Control Group
n=9 Participants
The control group did not receive any intervention. The patients in this group were assessed by the same reviewers (blinded to the study conditions) and under the same conditions, that patients in the experimental groups.
|
|---|---|---|---|
|
Changes in the Circumference of Arm
Pretreatment assessment
|
31.125 cm
Standard Deviation 3.144
|
31.331 cm
Standard Deviation 3.474
|
32.007 cm
Standard Deviation 3.837
|
|
Changes in the Circumference of Arm
Postreatment assessment
|
31.23 cm
Standard Deviation 3.22
|
31.72 cm
Standard Deviation 3.20
|
31.85 cm
Standard Deviation 3.56
|
|
Changes in the Circumference of Arm
Follow up assessment
|
31.02 cm
Standard Deviation 3.13
|
30.96 cm
Standard Deviation 2.70
|
31.68 cm
Standard Deviation 4.11
|
PRIMARY outcome
Timeframe: Screening visit (pretreatment assessment), postreatment evaluation (12 week) and follow up assessment (6 months after treatment)Population: It has made an analysis by intention to treat with the 27 patients included in the study
Measured by the breaking test for patients with haemophilia with a score from 0 to 5 (where 0 indicates normal strength and 5 is the absence of muscle contraction).
Outcome measures
| Measure |
Educational Gruop
n=9 Participants
The treatment had education and home daily exercises for the improvement of the range of motion, biceps strength, perimeter of arm and the perception of pain in patients with haemophilia and arthropathy of the elbow.
Educational group: - Theory: Introduction to hemophilia: clinic and treatment; Anatomy and biomechanics of elbow; Anatomy of elbow musculature. Function of muscles and haematomas treatment; Haemarthrosis, synovitis and arthropathy: clinical manifestations and treatment; Proprioception: definition and importance in hemophilia; and Physical activity and sport: risks and benefits.
\- Practice: exercises in favor of gravity; isometric and isotonic exercises of elbow; active exercises for mobility and pain management; elbow proprioception exercises; and swimming technique.
|
Manual Therapy Group
n=9 Participants
The treatment of this group consisted of two sessions per week, one hour each. We used joint traction, passive muscles stretching and Proprioceptive Neuromuscular Facilitation
Manual Therapy: - 5 minutes. Termotherapy shalow to 50 cm away from the elbow, using a bulb of 250w.
* 15 minutes. Joint traction of elbow, in submaximal mobility amplitude with distal fixation of humerus and proximal fixation of radius and ulna in neutral position of forearm. Joint traction in I-II degree of flexion and extension submaximal of elbow.
* 15 minutes. Passive muscle stretching (within the limits of mobility). Compression technique, passive muscle stretching and relaxation in biceps and triceps.
* 15 minutes. Proprioceptive neuromuscular facilitation (PNF) of upper limb.
* 10 minutes. Local cryotherapy with ice bag and protection between it and the skin
|
Control Group
n=9 Participants
The control group did not receive any intervention. The patients in this group were assessed by the same reviewers (blinded to the study conditions) and under the same conditions, that patients in the experimental groups.
|
|---|---|---|---|
|
Changes in Biceps Strength
Pretreatment assessment
|
0.000 points
Standard Deviation 0.000
|
0.094 points
Standard Deviation 0.272
|
0.143 points
Standard Deviation 0.363
|
|
Changes in Biceps Strength
Postreatment assessment
|
0.03 points
Standard Deviation 0.12
|
0.00 points
Standard Deviation 0.00
|
0.07 points
Standard Deviation 0.18
|
|
Changes in Biceps Strength
Follow up assessment
|
0.06 points
Standard Deviation 0.17
|
0.00 points
Standard Deviation 0.00
|
0.07 points
Standard Deviation 0.18
|
PRIMARY outcome
Timeframe: Screening visit (pretreatment assessment), postreatment evaluation (12 week) and follow up assessment (6 months after treatment)Using the visual analogue scale, VAS (subjective rating scale with a score from 0 to 10, where 0 indicates no pain and 10 the maximum pain imaginable by the patient).
Outcome measures
| Measure |
Educational Gruop
n=8 Participants
The treatment had education and home daily exercises for the improvement of the range of motion, biceps strength, perimeter of arm and the perception of pain in patients with haemophilia and arthropathy of the elbow.
Educational group: - Theory: Introduction to hemophilia: clinic and treatment; Anatomy and biomechanics of elbow; Anatomy of elbow musculature. Function of muscles and haematomas treatment; Haemarthrosis, synovitis and arthropathy: clinical manifestations and treatment; Proprioception: definition and importance in hemophilia; and Physical activity and sport: risks and benefits.
\- Practice: exercises in favor of gravity; isometric and isotonic exercises of elbow; active exercises for mobility and pain management; elbow proprioception exercises; and swimming technique.
|
Manual Therapy Group
n=8 Participants
The treatment of this group consisted of two sessions per week, one hour each. We used joint traction, passive muscles stretching and Proprioceptive Neuromuscular Facilitation
Manual Therapy: - 5 minutes. Termotherapy shalow to 50 cm away from the elbow, using a bulb of 250w.
* 15 minutes. Joint traction of elbow, in submaximal mobility amplitude with distal fixation of humerus and proximal fixation of radius and ulna in neutral position of forearm. Joint traction in I-II degree of flexion and extension submaximal of elbow.
* 15 minutes. Passive muscle stretching (within the limits of mobility). Compression technique, passive muscle stretching and relaxation in biceps and triceps.
* 15 minutes. Proprioceptive neuromuscular facilitation (PNF) of upper limb.
* 10 minutes. Local cryotherapy with ice bag and protection between it and the skin
|
Control Group
n=7 Participants
The control group did not receive any intervention. The patients in this group were assessed by the same reviewers (blinded to the study conditions) and under the same conditions, that patients in the experimental groups.
|
|---|---|---|---|
|
Changes in the Pain Perception of Elbow
Pretreatment assessment
|
0.156 points
Standard Deviation 0.301
|
0.719 points
Standard Deviation 0.752
|
0.143 points
Standard Deviation 0.305
|
|
Changes in the Pain Perception of Elbow
Postreatment assessment
|
0.09 points
Standard Deviation 0.20
|
0.34 points
Standard Deviation 0.43
|
0.07 points
Standard Deviation 0.67
|
|
Changes in the Pain Perception of Elbow
Follow up assessment
|
0.18 points
Standard Deviation 0.35
|
0.12 points
Standard Deviation 0.28
|
0.10 points
Standard Deviation 0.28
|
PRIMARY outcome
Timeframe: Screening visit (pretreatment assessment)Population: It has made an analysis by intention to treat with the 27 patients included in the study. It has been estimated the radiological joint damage means (and standard deviation) for elbow joint.
Pettersson scale is an additive scale that assesses the radiological joint damage in patients with hemophilic arthropathy. It is scored as a range of 0-13 points (0: no joint damage; 13: maximum joint damage). This scale assesses: osteoporosis, widened epiphyseal, irregularity of the chondral surface, joint space narrowing, subchondral cyst formation, joint margins erosion, joint incongruence and joint deformity (angulation and displacement)
Outcome measures
| Measure |
Educational Gruop
n=9 Participants
The treatment had education and home daily exercises for the improvement of the range of motion, biceps strength, perimeter of arm and the perception of pain in patients with haemophilia and arthropathy of the elbow.
Educational group: - Theory: Introduction to hemophilia: clinic and treatment; Anatomy and biomechanics of elbow; Anatomy of elbow musculature. Function of muscles and haematomas treatment; Haemarthrosis, synovitis and arthropathy: clinical manifestations and treatment; Proprioception: definition and importance in hemophilia; and Physical activity and sport: risks and benefits.
\- Practice: exercises in favor of gravity; isometric and isotonic exercises of elbow; active exercises for mobility and pain management; elbow proprioception exercises; and swimming technique.
|
Manual Therapy Group
n=9 Participants
The treatment of this group consisted of two sessions per week, one hour each. We used joint traction, passive muscles stretching and Proprioceptive Neuromuscular Facilitation
Manual Therapy: - 5 minutes. Termotherapy shalow to 50 cm away from the elbow, using a bulb of 250w.
* 15 minutes. Joint traction of elbow, in submaximal mobility amplitude with distal fixation of humerus and proximal fixation of radius and ulna in neutral position of forearm. Joint traction in I-II degree of flexion and extension submaximal of elbow.
* 15 minutes. Passive muscle stretching (within the limits of mobility). Compression technique, passive muscle stretching and relaxation in biceps and triceps.
* 15 minutes. Proprioceptive neuromuscular facilitation (PNF) of upper limb.
* 10 minutes. Local cryotherapy with ice bag and protection between it and the skin
|
Control Group
n=9 Participants
The control group did not receive any intervention. The patients in this group were assessed by the same reviewers (blinded to the study conditions) and under the same conditions, that patients in the experimental groups.
|
|---|---|---|---|
|
Assessment of Radiological Joint Deterioration
|
9.63 points
Standard Deviation 1.62
|
8.50 points
Standard Deviation 3.40
|
7.57 points
Standard Deviation 2.90
|
SECONDARY outcome
Timeframe: Screening visit (pretreatment assessment)Age of patients included in teh study (years)
Outcome measures
| Measure |
Educational Gruop
n=9 Participants
The treatment had education and home daily exercises for the improvement of the range of motion, biceps strength, perimeter of arm and the perception of pain in patients with haemophilia and arthropathy of the elbow.
Educational group: - Theory: Introduction to hemophilia: clinic and treatment; Anatomy and biomechanics of elbow; Anatomy of elbow musculature. Function of muscles and haematomas treatment; Haemarthrosis, synovitis and arthropathy: clinical manifestations and treatment; Proprioception: definition and importance in hemophilia; and Physical activity and sport: risks and benefits.
\- Practice: exercises in favor of gravity; isometric and isotonic exercises of elbow; active exercises for mobility and pain management; elbow proprioception exercises; and swimming technique.
|
Manual Therapy Group
n=9 Participants
The treatment of this group consisted of two sessions per week, one hour each. We used joint traction, passive muscles stretching and Proprioceptive Neuromuscular Facilitation
Manual Therapy: - 5 minutes. Termotherapy shalow to 50 cm away from the elbow, using a bulb of 250w.
* 15 minutes. Joint traction of elbow, in submaximal mobility amplitude with distal fixation of humerus and proximal fixation of radius and ulna in neutral position of forearm. Joint traction in I-II degree of flexion and extension submaximal of elbow.
* 15 minutes. Passive muscle stretching (within the limits of mobility). Compression technique, passive muscle stretching and relaxation in biceps and triceps.
* 15 minutes. Proprioceptive neuromuscular facilitation (PNF) of upper limb.
* 10 minutes. Local cryotherapy with ice bag and protection between it and the skin
|
Control Group
n=9 Participants
The control group did not receive any intervention. The patients in this group were assessed by the same reviewers (blinded to the study conditions) and under the same conditions, that patients in the experimental groups.
|
|---|---|---|---|
|
Characteristics of the Patients
|
33.78 years
Standard Deviation 15.72
|
32.33 years
Standard Deviation 11.67
|
37.33 years
Standard Deviation 12.26
|
SECONDARY outcome
Timeframe: Screening visit (pretreatment assessment)Number of elbow hemarthrosis in the month prior to study
Outcome measures
| Measure |
Educational Gruop
n=9 Participants
The treatment had education and home daily exercises for the improvement of the range of motion, biceps strength, perimeter of arm and the perception of pain in patients with haemophilia and arthropathy of the elbow.
Educational group: - Theory: Introduction to hemophilia: clinic and treatment; Anatomy and biomechanics of elbow; Anatomy of elbow musculature. Function of muscles and haematomas treatment; Haemarthrosis, synovitis and arthropathy: clinical manifestations and treatment; Proprioception: definition and importance in hemophilia; and Physical activity and sport: risks and benefits.
\- Practice: exercises in favor of gravity; isometric and isotonic exercises of elbow; active exercises for mobility and pain management; elbow proprioception exercises; and swimming technique.
|
Manual Therapy Group
n=9 Participants
The treatment of this group consisted of two sessions per week, one hour each. We used joint traction, passive muscles stretching and Proprioceptive Neuromuscular Facilitation
Manual Therapy: - 5 minutes. Termotherapy shalow to 50 cm away from the elbow, using a bulb of 250w.
* 15 minutes. Joint traction of elbow, in submaximal mobility amplitude with distal fixation of humerus and proximal fixation of radius and ulna in neutral position of forearm. Joint traction in I-II degree of flexion and extension submaximal of elbow.
* 15 minutes. Passive muscle stretching (within the limits of mobility). Compression technique, passive muscle stretching and relaxation in biceps and triceps.
* 15 minutes. Proprioceptive neuromuscular facilitation (PNF) of upper limb.
* 10 minutes. Local cryotherapy with ice bag and protection between it and the skin
|
Control Group
n=9 Participants
The control group did not receive any intervention. The patients in this group were assessed by the same reviewers (blinded to the study conditions) and under the same conditions, that patients in the experimental groups.
|
|---|---|---|---|
|
Frequency of Elbow Hemarthrosis
Hemarthros the month before the beginning of the s
|
1.06 bleeding events
Standard Deviation 1.23
|
1.06 bleeding events
Standard Deviation 0.68
|
0.71 bleeding events
Standard Deviation 0.91
|
|
Frequency of Elbow Hemarthrosis
Hemarthros during the study
|
0.00 bleeding events
Standard Deviation 0.00
|
0.00 bleeding events
Standard Deviation 0.00
|
0.62 bleeding events
Standard Deviation 0.87
|
Adverse Events
Educational Gruop
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Manual Therapy Group
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Control Group
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place