Reduction of Preoperative Anxiety in Children: Electronic Tab vs Midazolam

NCT ID: NCT02192710

Last Updated: 2025-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

118 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-05-31

Study Completion Date

2014-04-30

Brief Summary

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Rationale:

The most frequently used means to prevent pre-anaesthetic anxiety in children is a drug premedication. Midazolam, a benzodiazepine, is mainly used. It requires time for action, so coordination between departments and operating room, exposed to the risks of side effects and failure and this variability action. Alternative means were evaluated, such as the presence of parents during anaesthetic mask induction, distraction by clowns, hypnosis or video games.

Electronic tabs are small devices; light, easy to use with age-specific and interactive programs. Our hypothesis is that these electronic tabs are more effective in reducing anxiety and distract children compare to preoperative medication.

Methods: This is a monocentric, randomized, open-label study comparing patients aged 4 to 10 years old programmed for a short term and low level of pain outpatient surgery. My pass score will be measured when arriving at the hospital, at the time of the separation with the parents, at the time of the anaesthetic mask induction and after the surgery.

118 patients will be randomized as follows :

* Arm 1 : Hypnovel® (midazolam)
* Arm 2 : Electronic tab The recruitment is performed by general practitioners in the Lyon area.

Detailed Description

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Conditions

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Paediatric Outpatient Surgery

Keywords

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outpatient surgery anaesthesia midazolam electronic tab

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Hypnovel® (midazolam)

Midazolam oral intake before anesthesia

Group Type ACTIVE_COMPARATOR

Midazolam oral intake

Intervention Type DRUG

Electronic tab

Group Type EXPERIMENTAL

electronic tab

Intervention Type PROCEDURE

classic use of an electronic tab with age specific games

Interventions

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electronic tab

classic use of an electronic tab with age specific games

Intervention Type PROCEDURE

Midazolam oral intake

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Girls and boys aged 4 to 10 years,
* American Society of Anesthesiologists Score between 1 and 3,
* programmed outpatient surgery for a short term and low level of pain
* Infection with influenza A virus confirmed with a quick diagnostic test,
* informed consent from both parents

Exclusion Criteria

* patients younger than 4 or older than 10 years old
* preexisting psychiatric disorder with pedo-psychiatric follow-up
* children with intellectual disability
* psychotropic referred to anxiolytic and / or antipsychotic
* history of surgery (n\>=3)
* refusal to participate
Minimum Eligible Age

4 Years

Maximum Eligible Age

10 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Service d'anesthésie, Hôpital Femme Mère Enfant, Hospices Civils de Lyon

Bron, , France

Site Status

Countries

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France

References

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Marechal C, Berthiller J, Tosetti S, Cogniat B, Desombres H, Bouvet L, Kassai B, Chassard D, de Queiroz Siqueira M. Children and parental anxiolysis in paediatric ambulatory surgery: a randomized controlled study comparing 0.3 mg kg-1 midazolam to tablet computer based interactive distraction. Br J Anaesth. 2017 Feb;118(2):247-253. doi: 10.1093/bja/aew436.

Reference Type RESULT
PMID: 28100529 (View on PubMed)

Other Identifiers

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2013.794

Identifier Type: -

Identifier Source: org_study_id