A Multicenter, Post Marketing Clinical Follow up (PMCF) Investigation to Evaluate the Performance and Safety of a Soft Silicone Foam Dressing and to Evaluate the Performance of Standard Care in Exuding Venous Leg Ulcers

NCT ID: NCT02167815

Last Updated: 2016-10-26

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-05-31

Study Completion Date

2015-07-31

Brief Summary

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This investigation is a Post Marketing Follow-Up Study for Mepilex XT conducted as part of Mölnlycke Health Care's quality system. The primary objective is to evaluate the performance of the dressing when used as intended on exuding Venous Leg Ulcers (VLUs) in the inflammatory and granulating stages of the wound healing process.

Detailed Description

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Conditions

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Venous Leg Ulcer (VLU)

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Standard care

standard care ( such as alginate, hydrofiber or other treatment)

Group Type ACTIVE_COMPARATOR

standard care

Intervention Type OTHER

Intervention ( Mepilex XT)

Group Type EXPERIMENTAL

Mepilex XT

Intervention Type DEVICE

Experimental arm

Interventions

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Mepilex XT

Experimental arm

Intervention Type DEVICE

standard care

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Venous Leg Ulcer
2. Exuding wound
3. Wound surface covered with sloughy tissue\* (before debridement)
4. Wound size ≥ 6 cm2
5. In case of multiple wounds, target wound must be ≥ 3cm distant from other wounds.
6. Wound suitable for treatment with the relevant primary dressing\*\*
7. Male or female, 18 years of age and above
8. Signed Informed Consent

* Sloughy tissue defined as wet, yellow-brown fibrinous tissue present in the wound bed \*\* Mepilex XT in the intervention group. Standard care in the observation group

Exclusion Criteria

1. More than two products of 15 cm x15 cm needed to cover the whole wound and affected peri-wound area
2. Wound cavity and/or fistula
3. Full thickness burns
4. Exposed tendons and/or fascia
5. Bleeding wounds
6. Malignant or fungating wounds
7. Wound age \> 12 months
8. Use of antimicrobial dressings or topical agents such as antiseptics, local antibiotics and steroids within 7 days from inclusion on the wound intended to be included
9. Untreated limb ischemia (according to investigator's judgement) at the time of inclusion
10. Subject not suitable for the investigation according to the investigator's judgement
11. Subject included in other ongoing clinical investigation which could interfere with this investigation, as judged by the investigator
12. Known allergy/hypersensitivity to any of the components of the primary dressing
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Molnlycke Health Care AB

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Nemocnice Podlesí a.s.

Třinec, Konská 453, Czechia

Site Status

Nemocnice Jihlava

Jihlava, Vrchlického, Czechia

Site Status

The General University Hospital in Prague

Prague, , Czechia

Site Status

Countries

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Czechia

Other Identifiers

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RedEgg 01

Identifier Type: -

Identifier Source: org_study_id