Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
14 participants
OBSERVATIONAL
2013-09-30
2015-06-30
Brief Summary
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When normal conduction within the heart fails, the treatment may be to implant a permanent pacemaker. Pacing involves passing a lead via a vein to the heart and using an electrical impulse to stimulate a beat. The usual site for pacing is the tip of the RV. This has been shown to be less efficient than the normal conduction system of the heart and in some cases leads to markedly reduced function. What the investigators do not know is why this is the case.
Much effort has been directed at looking at features within the left ventricle (LV) for markers of disease progression but little has been investigated regarding the RV.
There may be some benefit to pacing the heart preferentially from different parts of the RV and the investigators aim to measure if any differences are detectable from stimulating the heart at various sites within the RV.
Detailed Description
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* Patients undergoing elective Electrophysiological Studies +/Ablation
* Age 18-80
* Normal Heart on Pre-procedural Echocardiogram
Exclusion criteria;
* Atrial Fibrillation
* Evidence of anterograde conducting accessory pathway
* Permanent Pacemaker insitu
* Pregnant
* Breast Feeding
Outcome Measures; Change in load-independent indices of LV and RV contractility before and after pacing intervention. LV and RV function measured by transthoracic echocardiography and tissue Doppler imaging.
Conditions
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Keywords
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Study Design
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CASE_ONLY
PROSPECTIVE
Study Groups
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Supra Ventricular Tachycardia (SVT)
Patients undergoing SVT studies
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Age 18-80
* Normal Heart on Pre-procedural Echocardiogram
Exclusion Criteria
* Evidence of anterograde conducting accessory pathway
* Permanent Pacemaker insitu
* Pregnant
* Breast Feeding
18 Years
80 Years
ALL
No
Sponsors
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Mid and South Essex NHS Foundation Trust
OTHER
Responsible Party
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Principal Investigators
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Stuart Tan
Role: PRINCIPAL_INVESTIGATOR
Basildon & Thurrock University Hospital NHS Trust
Locations
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The Essex Cardiothoracic Centre
Basildon, Essex, United Kingdom
Countries
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Other Identifiers
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B596
Identifier Type: -
Identifier Source: org_study_id