Trial Outcomes & Findings for Inhaled Nitrous Oxide for the Prevention of Emergence Reaction During Ketamine Administration in Adults, a Pilot Study (NCT NCT02145169)

NCT ID: NCT02145169

Last Updated: 2020-03-19

Results Overview

Presence or absence of emergence reaction

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

20 participants

Primary outcome timeframe

At primary ED visit when the patient is undergoing the intervention

Results posted on

2020-03-19

Participant Flow

0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

Participant milestones

Participant milestones
Measure
Nitrous Oxide Arm
Patients will receive a 50/50 mixture of Oxygen and Nitrous oxide via non breather mask Inhaled Nitrous Oxide: Patients undergoing procedural sedation with Ketamine will receive inhaled Nitrous Oxide
Overall Study
STARTED
0
Overall Study
COMPLETED
0
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Inhaled Nitrous Oxide for the Prevention of Emergence Reaction During Ketamine Administration in Adults, a Pilot Study

Baseline characteristics by cohort

Baseline data not reported

PRIMARY outcome

Timeframe: At primary ED visit when the patient is undergoing the intervention

Population: 0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

Presence or absence of emergence reaction

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: At primary ED visit when the patient is undergoing the intervention

Population: 0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

ETCO2 measured q 5 seconds

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: At primary ED visit when the patient is undergoing the intervention

Population: 0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

SpO2 measured q 5 seconds

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: At primary ED visit when the patient is undergoing the intervention

Population: 0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

heart rate, respiratory rate, peripheral SaO2

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: At primary ED visit when the patient is undergoing the intervention

Population: 0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

verbal or physical stimulation, airway repositioning, additional oxygen, positive pressure ventilation, endotracheal intubation

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: At primary ED visit when the patient is undergoing the intervention

Population: 0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

Ramsay sedation score

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: At primary ED visit when the patient is undergoing the intervention

Population: 0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

Patient recall of procedure

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: At primary ED visit when the patient is undergoing the intervention

Population: 0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

Total Ketamine dose

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: At primary ED visit when the patient is undergoing the intervention

Population: 0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

Total elapsed time of nitrous use

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: At procedure completion

Population: 0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

Physician procedure satisfaction survey responses

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: At procedure completion

Population: 0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

Patient procedure satisfaction survey responses

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: At procedure completion

Population: 0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

Nurse procedure satisfaction survey responses

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: At primary ED visit

Population: 0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

Length of ED stay

Outcome measures

Outcome data not reported

Adverse Events

Nitrous Oxide Arm

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Kamran Mohiuddin. Director Clinical Research Emergency Department

Albert Einstein Medical Center

Phone: 2154562313

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place